Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2. Journal of Medicinal Chemistry (2007), 50(17), 3984-4002.
Parallel strategies for the preparation and selection of liver-targeted glucocorticoid receptor antagonists. Bioorganic & Medicinal Chemistry Letters (2007), 17(1), 40-44.
A stereoconvergent strategy for the synthesis of enantiomerically pure (R)-(-)- and (S)-(+)-2-(6-methoxy-2-naphthyl)propanoic acid (naproxen). Tetrahedron (1989), 45(13), 4243-52
看看吧，可能有用
artaric acid, an efficient chiral auxiliary: new asymmetric synthesis of 2-alkyl-2-arylacetic acids. Journal of Organic Chemistry (1987), 52(14), 3018-27，
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用对羟甲基苯乙酮，先把羟基保护起来做。最后把保护基脱了，氢溴酸溴化
能具体 点吗 看不懂
去请牛人帮忙找找SCI有没有啊 ，或者类似的文献。
调整了一下顺序。跟上面的描述有点出入。不知道是否可行。
[ Last edited by saki6175 on 2010-5-31 at 19:20 ]
Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2. Journal of Medicinal Chemistry (2007), 50(17), 3984-4002.
Parallel strategies for the preparation and selection of liver-targeted glucocorticoid receptor antagonists. Bioorganic & Medicinal Chemistry Letters (2007), 17(1), 40-44.
A stereoconvergent strategy for the synthesis of enantiomerically pure (R)-(-)- and (S)-(+)-2-(6-methoxy-2-naphthyl)propanoic acid (naproxen). Tetrahedron (1989), 45(13), 4243-52
看看吧，可能有用
artaric acid, an efficient chiral auxiliary: new asymmetric synthesis of 2-alkyl-2-arylacetic acids. Journal of Organic Chemistry (1987), 52(14), 3018-27，
氯苄要自身烷基化 这个反应较难实现
苄氧基钝化苯环的 第一个反应较难