关于肝微粒体代谢的四个问题，谢谢！
问题1：You studied specific isoforms of CYP. Are you sure that these CYP isoforms are specifics to these biological activities?
问题2：- On the page 5, you precised that you added acetonitrile to stop the reaction. Why did you not use an acid to stop the reaction?
问题3：-Why UGT substrates were pre-incubated before inhibition with psoralidin
问题4：-Similarly, was there any pre-incubation of substrates or inhibitors for UGTs and CYPs? How long? And why?. Needs to be clarified in the text.
reviewer的4个问题，谢谢！
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你的文章啥内容啊？光贴出意见，怎么帮你忙？
都不是大问题 自己实验室内部讨论一下 应该就能解决了吧 要不就去问问老板。另外同楼上，这种细节问题不了解内容无法下定论。
类似专业的问题建议楼主先给导师，或者同方向的师兄师姐看看。
请教一下，肝微粒体跟实际肝脏中的代谢有什么区别呀？肝微粒的构建能不能指导一下，本人正想构建一个体外的肝微粒系统，有没有文献推荐一下，或者将您的经验告知一下。膜拜！！！
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细节问题。问问实验室老师师兄师姐。应该就能解决。