二审结果大修，三个审稿人同意接受，只有一个审稿人又给大修但没有具体意见怎么办？
主编亲自回复的邮件，差点被直接毙了。
Reviewers have now commented on your paper. You will see that they are advising that you revise your manuscript. If you are prepared to undertake the work required, I would be pleased to reconsider my decision.
Reviewer #1: The authors have covered all my comments, feedback, suggestions and concerns. I have no additional comments and I am now happy that the revised manuscript to be accepted.
Reviewer #4: Major revise
The manuscript needs some revisions by journal experts
The corrections made have no significant improvement on the paper.
各位大神，请问怎么办啊？已经写好了申诉信并向主编询问审稿人4#具体哪里不满意，我再改正。但是感觉是然并卵。各位有其他高招吗？
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我又找专家润色了语言，然后申诉了，据理力争。昨天接受了
，
当然最好再看看审稿人最初的意见，想想是否有回答不到位或不全面的地方。最好拿出相关文献支撑。