Synthesis of Main Impurity of Vildagliptin

作者:Tao, Z (Tao, Zhu)[ 1 ] ; Deng, Y (Deng, Yu)[ 1 ] ; Chen, YJ (Chen, Yingjie)[ 1 ] ; Wang, AM (Wang, Anmin)[ 1 ] ; Hu, XN (Hu, Xiangnan)[ 1 ]

ASIAN JOURNAL OF CHEMISTRY

卷: 26

期: 12

页: 3489-3492

子辑: B

出版年: JUN 2014

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摘要

A four-step synthesis of the main impurity of vildagliptin has been easily accomplished with high-yielding starting from L-proline. This compound can be used as a reference marker in an analytical method to determine the chemical purity of the vildagliptin.
关键词

作者关键词PP-IV inhibitors; Vildagliptin; L-proline; Impurity

KeyWords Plus:TYPE-2 DIABETES-MELLITUS; DIPEPTIDYL PEPTIDASE-4 INHIBITOR; SAXAGLIPTIN; SITAGLIPTIN; ALOGLIPTIN; THERAPY
作者信息

通讯作者地址: Hu, XN (通讯作者)
[显示增强组织信息的名称]         Chongqing Med Univ, Coll Pharmaceut Sci, Chongqing 400016, Peoples R China.

地址:
[显示增强组织信息的名称]         [ 1 ] Chongqing Med Univ, Coll Pharmaceut Sci, Chongqing 400016, Peoples R China

电子邮件地址:huxiangnan62@163.com
基金资助致谢
基金资助机构        授权号
Natural Science Foundation of Chongqing (CSTC)        
2006BB5286
Chongqing Medical University          
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出版商

ASIAN JOURNAL OF CHEMISTRY, 11/100 RAJENDRA NAGAR, SECTOR 3,, SAHIBABAD 201 005, GHAZIABAD, INDIA
类别 / 分类

研究方向:Chemistry

Web of Science 类别:Chemistry, Multidisciplinary
文献信息

文献类型:Article

语种:English

入藏号: WOS:000343762400011

ISSN: 0970-7077

eISSN: 0975-427X
期刊信息

    Impact Factor (影响因子): Journal Citation Reports®

其他信息

IDS 号: AR7LY

Web of Science 核心合集中的 "引用的参考文献": 23

Web of Science 核心合集中的 "被引频次": 0，

Cloning and Characterization of Glyceraldehyde-3-Phosphate Dehydrogenase from Orchid (Cymbidium goeringii)  

저자: Tian, Yun-Fang; Li, Han; Yuan, Xiu-Yun; 등등.

ASIAN JOURNAL OF CHEMISTRY  권: 26   호: 17   페이지: 5321-5323   부: A   출판연도: SEP 2014

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