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N,N-Dimethyl-L-phenylalanine合成路线求助

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N,N-Dimethyl-L-phenylalanine合成路线求助

CAS号:17469-89-5 返回小木虫查看更多

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  • liujiang19-6

    买啊

  • w87437985

    合成路线:
    1.通过甲醛和L-苯丙氨酸合成N,N-二甲基-L-苯丙氨酸,收率约91%;

    如果用量不大,建议购买

  • w87437985

    Add 165g of L-phenylalanine to 2 liters of ethanol, add 243ml of aqueous formaldehyde solution (37%), slowly at 0 degreesAdd a solution of 114 g of sodium borohydride dissolved in 1 liter of ethanol, control the temperature below 20 degrees, add dropwise after 2 hours, and stir for 8 hours.The reaction was detected to be complete. The pH was adjusted to 4-5 with 6N hydrochloric acid, the ethanol was concentrated, and the residue was extracted with ethyl acetate.Dried and concentrated to obtain 180g of product,The content is 98%, and the yield is 93.2%,

  • czyzsu

    sf检索结果链接: https://pan.baidu.com/s/1fswQWfkP6KolYpDhIB_Qhg 提取码: s93d ,希望对你有所帮助!

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