ÕÐƸְλ: Postdoctoral Fellow
ÕÐƸÁ´½Ó: https://www.vcujobs.com/postings/103386
½ØÖ¹ÈÕÆÚ: open until filled
ÕÐƸ·½Ïò: Chemical Biology
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¹¤×÷µØµã: ¸¥¼ªÄáÑÇÀïÊ¿Âú (Richmond, VA)

A Chemical Biology postdoctoral fellow position is available in Dr. Yana Cen¡¯s lab in the Department of Medicinal Chemistry at Virginia Commonwealth University (VCU)-MCV Campus. Our research aims to understand the roles of mammalian enzymes play in physiological and pathological processes and to use this knowledge to identify novel therapeutic targets for the treatment of human diseases. In particular, we are interested in a class of epigenetic modification enzymes called sirtuins, which are involved in protein post-translational modification and have important biological functions. We take a highly integrative chemical biology approach to study the enzymology, identify the modified protein targets, and study the biological significance of the modification. We also develop small molecule regulators targeting these enzymes as therapeutics for age-related diseases and cancer.

The ideal candidate should have a PhD in Biochemistry, Molecular and Cellular Biology, Chemical Biology or a related discipline, and have experience with genetically engineering bacteria, protein purification, enzymatic assays as well as cell biology techniques. Additional knowledge of the following techniques is highly desirable: isothermal titration calorimetry (ITC), Mass Spectrometry and/or X-ray crystallography. The successful applicant will have a strong scientific record, excellent communication skills, ability to work independently and as part of team, and willingness to help mentor junior scientists.

VCU offers an excellent benefits package and a competitive salary commensurate with qualifications and experience. The initial appointment will be for a one-year period, with the possibility of an extension depending on performance and availability of funding. Review of applications will begin immediately and continue until the position is filled. Interested applicants should email cover letter describing research experience and interests, CV with publication list, and contact information of three references to:

Yana Cen, PhD
Assistant Professor
Department of Medicinal Chemistry
Virginia Commonwealth University
800 E Leigh Street, Suite 212
Richmond, VA 23219
ceny2@vcu.edu
804-828-7405 ·µ»ØСľ³æ²é¿´¸ü¶à