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Katsonis½ÌÊÚ×öµÄÊÇÉúÎïÓëÏìÓ¦ÐͲÄÁÏ£¬¾ßÓл¯Ñ§¡¢²ÄÁÏÒÔ¼°ÉúÎï±³¾°µÄͬѧ¶¼¿ÉÒÔͶ¼òÀú¡£ Katsonis½ÌÊÚÊÇLZµ±Ê±¶ÁÊéʱ×éÀïµÄ²©ºó£¬È˳¬¼¶nice, ¶øÇÒËý»¹Í¬Ê±»ñµÃºÉÀ¼ÑŵäÄȽܳöÅ®ÐÔ¿ÆÑ§¼Ò½±£¬¿ÎÌâ×龷ѳä×ã¡£ ¶øÇҹؼüÊÇ£¬ÎÄÕ·¢µÃ³¬ºÃ£¡²©Ê¿Éú¶¼ÄÃ×Å2ƪ1Çø±ÏÒµµÄ£¬»ù±¾ÉÏÿÄê¶¼ÓÐnature ×Ó¿¯¡£Ç¿ÁÒÍÆ¼ö£¬±£Ö¤ÄÃןÃÎÄÕ±ÏÒµ¡£½¨Òé´ó¼ÒͶ¸ö¼òÀúÎÊÎÊ¡£
ËýµÄ¿ÎÌâ×éÍøÕ¾www.katsonis.eu
ËýµÄÓÊÏ䣺 n.h.katsonis@rug.nl
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The functional movement of living plants, animals, and other organisms is supported by molecules that in themselves move randomly. We are working to uncover how motion can be observed in purely synthetic systems, with the long-term goal of understanding what is different about living and non-living matter. Our strategy often draws inspiration from engineering strategies seen in biology, where molecular machines maintain out of equilibrium states by ingenious coupling with their anisotropic environment.
Shape-generating chemistry. In one of our seminal works we have reported how the interplay between asymmetry by gradients and anisotropy of e.g. liquid crystals, combined with the mechanically relevant motion of molecular switches, encodes the conversion of light into helical movement. Ultimately, artificial shape-generating systems may help untangle physical and chemical underpinnings of shape evolution and contribute to the design of life-like materials.
Motile behavior of minimal life forms. The movement of cells is essential to the operation of living matter. We are working toward incorporating complex motile behavior into synthetic mimics of minimal life-forms, by coupling molecular chemistry to physical processes. A theme of this program is to make droplets, vesicles or other micro compartments that move autonomously by using metabolic energy.
Selected Publications:
o N. Katsonis, F. Lancia, D. A. Leigh, L. Pirvu, A. Ryabchun, F. Schaufelberger ¡°Knotting a molecular strand can invert macroscopic effects of chirality.¡± Nat. Chem. 2020, 12, 939¨C944.
o F. Lancia, A. Ryabchun, N. Katsonis ¡°Life-like motion driven by artificial molecular machines¡± Nat. Rev. Chem. 2019, 3, 536¨C551
o F. Lancia, A. Ryabchun, A-D. Nguindjel, S. Kwangmettatam, N. Katsonis ¡°Mechanical adaptability of artificial muscles from nanoscale molecular action¡± Nat. Commun. 2019, 10, 4819
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