求助！论文投稿后修回的reviewer意见，完全不知道怎么回复？求大神帮忙，急！这里提到的signal是我做组化的结果。reviewer质疑测到的蛋白是否是内源性的蛋白，我不知道怎么证明。
How did the authors confirm that these signals really came from endogenous enzymes? In general, it is quite tough to detect endogenous glycosyltransferases, because the expression levels are low and we get many non-specific signals.

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