收录证明需要去专门的机构开！比如学校图书馆

Accuracy of microRNAs for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis
作者:He, S (He, Song)[ 1 ] ; Hu, XW (Hu, Xiao-Wu)[ 1 ] ; Wang, D (Wang, Dong)[ 1 ] ; Han, LF (Han, Ling-Fei)[ 1 ] ; Zhang, DC (Zhang, De-Chun)[ 2 ] ; Wei, C (Wei, Cheng)[ 1 ]
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
卷: 40  期: 4  页: 405-417
DOI: 10.1016/j.clinre.2016.02.001
出版年: SEP 2016
文献类型:Review
查看期刊影响力
摘要
Due to the high morbidity, mortality and late detection of hepatocellular carcinoma (HCC), it becomes a major public health challenge. MicroRNAs (miRNAs) have been reported to be aberrantly expressed in patients with HCC and thus may serve as potential diagnostic biomarkers. The aim of this study was to systematically assess the diagnostic accuracy of miRNAs as biomarkers for diagnosing HCC through a meta-analysis. Our results indicated that serum miRNAs had a relatively high diagnostic value for HCC diagnosis; the combination of serum 0:fetoprotein (AFP) and miRNAs displayed a better diagnostic accuracy than using AFP or miRNAs alone; the combination of multiple miRNAs assay in serum had the highest diagnostic accuracy in HCC diagnosis based on the published data. In conclusion, our meta-analysis suggests that miRNAs, especially serum miRNAs, had a relatively high diagnostic value for HCC diagnosis, which can discriminate HCC from healthy subjects and those with chronic hepatitis and cirrhosis easily, and may serve as a novel, less-invasive screening tool. (C) 2016 Elsevier Masson SAS. All rights reserved.
关键词
KeyWords PlusOTENTIAL BIOMARKER; CANCER STATISTICS; CHRONIC HEPATITIS; PERFORMANCE; RISK
作者信息
通讯作者地址: He, S (通讯作者)
              Maanshan Municipal Hosp Grp, Maanshan Ctr, Clin Lab, 45 Hubei Rd, Maanshan 243000, Peoples R China.
地址:
              [ 1 ] Maanshan Municipal Hosp Grp, Maanshan Ctr, Clin Lab, 45 Hubei Rd, Maanshan 243000, Peoples R China
显示更多        [ 2 ] Chongqing Med Univ, Mol Med & Tumor Res Ctr, Chongqing 400016, Peoples R China
电子邮件地址:jarm190@163.com
基金资助致谢
基金资助机构        授权号
Maanshan Municipal Public Health Bureau          
查看基金资助信息   
出版商
ELSEVIER MASSON, CORPORATION OFFICE, 65 CAMILLE DESMOULINS CS50083 ISSY-LES-MOULINEAUX, 92442 PARIS, FRANCE
期刊信息
Impact Factor (影响因子): Journal Citation Reports
类别 / 分类
研究方向:Gastroenterology & Hepatology
Web of Science 类别:Gastroenterology & Hepatology
文献信息
语言:English
入藏号: WOS:000388875200013
PubMed ID: 27016891
ISSN: 2210-7401
eISSN: 2210-741X
其他信息
IDS 号: ED5EU
Web of Science 核心合集中的 "引用的参考文献": 44
Web of Science 核心合集中的 "被引频次": 7，