We note that your manuscript contains tables that may be more appropriately placed in SUPPORTING INFORMATION in accord with the policy described below.  We ask you to consider what should be placed in SUPPORTING INFORMATION and be prepared to reformat your manuscript accordingly. Please wait until the review process is completed and revision is requested to make these changes.  Of course, this should be done at the outset for any future submissions.  Our editorial team will base decisions on manuscript acceptance with this objective in mind.

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