plos one 投稿两个月，今天有了回复，这是本人第一次投稿，经常看到大家说大修小修，可是我的修回意见没有明确说明是大修还是小修。审稿人的问题基本都可以回答，除了涉及样本量比较麻烦之外。麻烦大家帮忙鉴定这是大修还是小修，谢谢大家了。
Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised by the three reviewers.

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