法国巴黎综合理工大学招聘博士后
如题,
Bastien Nay 研究员课题组,明年一月份去巴黎综合理工大学(欧洲最好的理工大学之一)上任,现需要博士生和博士后,有意向请直接联系Bastien Nay研究员或通过我推荐。(今年的CSC博士生1月初申请截止,博士后2月申请截止)
另我有招生简章,可是上传出现乱码,有意者尽快发简历!
课题组链接:
https://naygroup.wordpress.com/
我的邮箱:lxwlxw1234@163.com
返回小木虫查看更多
今日热帖
京公网安备 11010802022153号
这个对专业有要求吗
不是这个方向的 好地方
有机化学,药物化学或化学生物学,不好意思没有写明!
有机化学,药物化学或化学生物学,不好意思没有写明!
Research Topic for the ParisTech/CSC PhD Program
Subfield: Organic chemistry
ParisTech School: Ecole Polytechnique
Title: Combining biomimetic and diversity-oriented strategies to synthesize natural products and medicinally relevant analogues in the aurachin series
Advisor(s):
Dr. Bastien Nay, bastien.nay@polytechnique.edu, https://naygroup.wordpress.com/
Short description of possible research topics for a PhD:
In 2013 we described the first total synthesis of aurachin D and analogues, and found potent inhibitory properties on the mitochondrial respiratory chain.1 Based on Müller's biosynthetic hypotheses, we also investigated the reactivity of our aurachin analogues in the presence of one of the aurachin biosynthetic enzymes, leading to new biosynthetic hypotheses involving a cascade of retro-[2,3]Wittig and Claisen rearrangements instead of the originally suggested pinacol rearrangement.2 Based on these findings, this PhD project aims at developing bio-inspired strategies to synthesize aurachins B and C. Diversity-oriented and function-oriented strategies will be applied in order to (1) build a medicinally relevant library of compounds and test it on relevant biological targets, and (2) simplify the aurachin core to the essential elements for biological activities (e.g. a shorter geranyl derivative has the same activity as the original farnesyl). In addition, a final level of diversity (and complexity) will be obtained through bio-inspired photooxygenated processes currently developed in our group. Overall the methodological aspects of organic synthesis will gain from our biosynthetic hypothesis to be synthetically challenged, since unprecedented chemical rearrangements (i.e. retro-[2,3]Wittig) with potentially high impact are expected to be unveiled by this work.
Required background of the student: The PhD applicant should have a Master degree in organic chemistry and a strong interest in organic synthesis and synthetic methodologies. A high level of spoken and written English is also expected. An interest in biosynthetic pathways and chemical biology would be appreciated
,
刚回复你的是博士生,博士后就是有机化学和药物化学!
具体你可以和Bastien Nay教授直接联系询问,附上你的简历!也可以先把简历给我看看把把关,推荐一下!