Postdoctoral Research Fellow in Synthetic Medicinal Chemistry

Postdoctoral researcher positions are available in the Zhu group at Department of Chemistry, University of Texas at El Paso (UTEP), to develop small molecule drug candidates of novel actions for targeted cancer and cardiovascular disease therapies. The Zhu Group website is: https://science.utep.edu/zhu/ .

Dr. Yaoqiu Zhu got his Ph.D. with Professor Richard Silverman (inventor of Pfizer's blockbuster drug Lyrica) in Northwestern University. He then joined Abbott Laboratories as a medicinal chemistry research scientist and made direct contributions to the recently launched HCV drug Viekira Pak. After resigned from Abbott, he founded his own research laboratory and published a series of independent papers on major ACS journals about the clinical drawbacks of the cardiovascular blockbuster drug Plavix and developed novel drug candidates. Recently Dr. Zhu started his new career as an assistant professor at UTEP, focusing on developing new methodologies for biomedical research and drug discovery.

The Zhu group is seeking highly motivated synthetic medicinal chemistry post-doc to join the new laboratory. The Zhu Group research covers medicinal chemistry, bioorganic chemistry, biochemical pharmacology, structural biochemistry, computer modeling, biological assays and animal studies, ADEM/PK/Tox tests, etc. The major therapeutic focuses are cancer and cardiovascular diseases. The successful candidate will be involved in the design and synthesis of small molecule drug candidates with novel action modes for targeted and personalized treatments. The duties will include design and synthesis of new analogues of established leads to develop biologically active compounds for testing in in vitro systems and in animals.

The candidate must be proficient in designing synthetic routes and solving challenging problems in multi-step synthesis. The candidate also needs to have medicinal chemistry knowledge including: ligand-receptor interactions such as reversible kinetics and irreversible modification, structure-based drug design, SAR exploration, parallel and library synthesis, computer modeling, biological tests including cell line assay and in vivo studies, etc.

Please submit a brief cover letter, CV with contact information of 2-3 references, and a summary of research accomplishments combined in one PDF file to: yzhu2@utep.edu. 返回小木虫查看更多