之前发表过一篇关于Amyloid self-assembly (蛋白自组装）的文章，做这方面的大家来看一看，如果觉得不错就引用一下吧。很像让更多的人看到我的研究。

可以引用的关键词： amyloid, self-assembly, material, Alzheimer, macro-molecule, kinetics, infrared spectroscopy, solid state NMR


蛋白自组装过程是可逆的，组装成一个形态之后还会随着时间的变化演变成另一种形态，所以蛋白组装的过程，时间，环境也极其重要。

摘要：
In contrast to an expected Ostwald-like ripening of amyloid assemblies, the nucleating core of the Dutch mutant of the Aβ peptide of Alzheimer’s disease assembles through a series of conformational transitions. Structural characterization of the intermediate assemblies by isotope-edited IR and solid-state NMR reveals unexpected strand orientation intermediates and suggests new nucleation mechanisms in a progressive assembly pathway.

原文链接 https://pubs.acs.org/doi/abs/10.1021/ja508621b



引用到SCI的宝宝们请跟我联系，免费给你们下5篇文献。

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