Ref.: JCB-15-900
Title: Pharmacokinetics study of 3,4-divanillyltetrahydrofuran in rats by ultra-flow liquid chromatography-tandem mass spectrometry
Corresponding Author: Mr. Xiaobing Cui

Dear Mr. Cui,

On behalf of the editor handling your manuscript, Dr. David S. Hage, I am writing to you in reference to your manuscript entitled:


As you will see from the comments appended below, a major revision has been requested. I should be grateful if you would revise the paper in accordance with these recommendations and submit your revised manuscript within 60 days.

Please submit your suitably revised manuscript online by logging onto https://ees.elsevier.com/chromb/

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1. A detailed, point-by-point response to each comment raised in the review. Please list each comment from this review, one by one, and provide your reply below each comment, including the actual changes made in the manuscript and their location (or the reason why no change was made). Useful information in the reply letter that answers a reviewer's comment needs to be included in the manuscript as well.  This document should be uploaded as "Response to Reviewer Comments".

2. A complete, editable, electronic copy (i.e. Word, WordPerfect, RTF, or LaTex) of the revised manuscript in which all the changes made in response to these comments are clearly indicated with red highlight. This document should be uploaded as "Manuscript".  Please do NOT upload any other copies of the manuscript.

3. Figures should be uploaded individually as TIF or EPS files with the figure number clearly indicated in the file name.

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Please note that we allow 60 days for the first author revision and 30 days for any additional author revisions that are required.

Thank you for your cooperation.

Journal of Chromatography B features the Interactive Plot Viewer, see: https://www.elsevier.com/interactiveplots. Interactive Plots provide easy access to the data behind plots. To include one with your article, please prepare a .csv file with your plot data and test it online at https://authortools.elsevier.com/interactiveplots/verification before submission as supplementary material.

We look forward to receiving your revised manuscript.

Kind regards,

David S. Hage, PhD
Editor
Journal of Chromatography B


Comments:

Editor: This paper needs some revisions in its English and grammar usage before I can send it to external reviewers. I recommend that the authors have someone who is an expert or proficient in English writing to go carefully through this article to proofread and correct it as the authors' revise this paper.

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