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[求助] 求一段FRET相关研究内容的翻译，谢谢

我是做图像处理的，现在被要求与生物传感结合，老板给的文章，实在是看不懂。麻烦做生物医学或相关的朋友帮忙翻一下下面一段话，感之不尽。

Based on fluorescent resonance energy transfer (FRET), several genetically encoded biosensors for detecting the spatiotemporal activities of signaling molecules have been developed, including Src, Rac1, MT1-MMP, and Calcium. With a Src biosensor, local mechanical stimulation induced by laser-tweezer-traction can be observed to cause a directional wave propagation of Src activation along the plasma membrane. Different Src activities can also be observed at different sub-compartments when the Src biosensor is tethered on plasma membrane in or outside of lipid raft. A Rac biosensor further revealed that the Rac activity in cells constrained on micropatterned extracellular-matrix surface is polarized with higher activity concentrated at the leading edge of migrating cells upon PDGF stimulation, whereas Src activities in these cells displayed global activation patterns without obvious polarity. With a MT1-MMP biosensor, epidermal growth factor (EGF) can be observed to induce significant FRET changes in live cancer cells expressing MT1-MMP, but not in MT1-MMP-deficient cells. Active MT1-MMP was directed to the leading edge of migrating cells along micropatterned fibronectin stripes, via a process dependent upon an intact cytoskeletal network. Most recently, our calcium biosensor revealed that there is a spontaneous Ca2+ oscillation in human mesenchymal stem cells (HMSCs) both inside the cytoplasm and endoplasmic reticulum (ER). The substrate stiffness where HMSCs are cultured can significantly affect this Ca2+ oscillation, in a fashion dependent on the RhoA signaling pathway.

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