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µÚÒ»´ÎͶ¸åSCI£¬¾ÍÔâµ½Ð޸ĺóÖØÐÂͶ¸åµÄ´ò»÷¡£Éó¸åÈËÌá³öÏÂÁÐÒâ¼û¡£Ã»¿´Ì«Ã÷°×¡£Çë´ó¼Ò°ïæ·ÖÎö¡£ Dear Authors, The proposed methodology may lays a foundation in synthesising pyrazolo-pyrimidine derivatives which were acknowledged among the important biologically active compounds. To further improve this works, it is suggested to: 1) Differentiate between the proposed and available methods and highlight how the proposed works can bridge the limitation of current research. 2) Provide the relevency of the choosen alkoxy and aromatic system. 3) Extend the research framework and show the versatility of the proposed methods and its tolerancy towards different funcionalities. 4) Design the research by not varying the substituents which posses similar trend. The strength of this report is due to its potential as convenience methodology albeit need to further establish the proof-of-concept. On the positive notes, the report was written in adequate manners with support from relevance literatures, using acceptable scientific language, the postulated reaction mechanism were cleary explained and the compounds were characterized accordingly. All the best |
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