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Thank you for submitting your manuscript to The ISME Journal. Your manuscript was reviewed by several experts in the field; and we are enclosing the comments they have made. As you can see, the reviewers think that the work is of potential interest; however, significant concerns have also been voiced, which would preclude publication of the paper in its present form.

We are willing to consider a revised version of the manuscript providing that you satisfy the criticisms raised in the attached comments by the reviewers and/or the Editors. The manuscript requires a thorough revision and as you can see from the comments that most points raised are straight forward to consider. I would agree with referees #1 and #3 that you need to make the effort to better explain the methods and reasoning behind your experimental/cultivation design and consider related studies. Please also comment on the origin of the strain.
Generally, a revised manuscript should be re-submitted within 1 month. Additional time for revision may be granted to the authors upon request. Please inform the editorial office immediately if you anticipate need for such an extension.
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3¡¢reject the manuscript, typically on grounds of specialist interest, lack of novelty, insufficient conceptual advance or major technical and/or interpretational problems.

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