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zhtear99
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11Â¥2012-11-29 19:21:32
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1) It is better to add some new references, which can make reviewer to know the recent research and the innovations. 2) the innovations should be described clearly. 3) The English should be polished by a native English speaking person. ·¢Ò»¸ö¸ø´ó¼Ò²Î¿¼£¬Ï׳óÁË |
18Â¥2012-11-29 19:46:33
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The authors complemented their manuscript and provided an adequate justification of the results obtained in the paper in response to the reviewer comments. I believe the revised version can be accepted for publication after the following minor revisions: 1. A clear presentation of the novelty of the paper in the introduction, especially in relation to references 33 and 34. 2. Determination of the amount (%) of D-units in the PLA chain. The D- and L-content are fundamental for the crystallization behavior of PLA and absolutely necessary in a publication like the present one. |
27Â¥2012-11-29 22:13:35
okitworks
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zhtear99: ½ð±Ò+8, ллok°æÀ´¸å£¬¹þ¹þ~ 2012-11-30 17:26:43
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45Â¥2012-11-30 16:47:35
myIDname
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zhtear99: »ØÌûÖö¥ 2012-12-01 10:42:25
zhtear99: ½ð±Ò+10, ¸Ðл¹ËÎÊͯЬÌṩµÄÉó¸åÒâ¼û£¬·Ç³£ÍêÕû£¬»¹ÓÐ×Ô¼ºµÄÆÀ¼Û£¬ºÜ°ô~ 2012-12-01 13:01:29
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Ñо¿·½Ïò£ºMEMS£¨microelectro-mechanical systems£© Éó¸åÒâ¼û£ºÈçÏÂËùÁÐ ¸öÈ˸ÐÏ룺µÚ¶þ¸öreviewer¿´ËÆÓеãΪÄÑÎÒÃÇ£¬ÌáÁ˺ܶà±È½ÏµóÄÑÈ˵ÄÎÊÌ⣬µ«ÊÇÕæµÄºÜÓаïÖú£¬ÓÈÆäÊǶÔÓÚÈçºÎÔÚÒѾÓÐÁ˺õÄideaµÄÇé¿öÏ£¬Ôõôʰ빦±¶Ö¤Ã÷Õâ¸öideaƯÁÁ¡£ºóÀ´ÎÒÃǻظ´Ö®ºó£¬Õâ¸öreviewer»¹ÓÖÀ´ÁËÒ»¸öÎÊÌ⣬ËùÒÔ»¹Óеڶþ´Î´ð¸´¡£×îÖÕreviewer¿ÉÄܱȽÏÂúÒâ°É£¬¸øÎÒÃÇÎÄÕ´ò·Ö±È½Ï¸ß£¬×îºó±»ÊÕµ½ÁËÔÓÖ¾µÄÄê¶ÈhighlightÀïÃæ£¨ÏÔ°Úһϣ¬Ö»ÓÐ3%µÄÎÄÕ±»ÊÕ¼ÁË £©Referee report First referee's report The concept is very interesting. The manuscript is very well written. The conclusions are supported by experimental data. Of course a good job! Second referee's report This work presents a new exciting idea to develop a XXX which has good potential. Authors have however failed to demonstrate clearly the benefits of their device. In Figure 7 the slope of the straight heated and XXX heated curve look very similar except for probably initial 2-3 secs. The two cooling mechanisms look to saturate at two different temperatures. It means that the thermal resistances of the two systems are different and are hence not completely comparable. The absolute difference in final temperature is of little consequence as a different heat-sink for the straight cooled device can reach the similar final temperature with a similar time delay. The benefit of the presented device is that it will allow any MEMS device to reach its final operating temperature quickly with minimal energy loss and then maintain the operating temperature. So it is recommended that the authors comment of the initial slope of the two curves (or compare the energy lost in reaching the final state) and compare their device with respect to the straight cooled device. Authors can also consider devicing an experiment in which both the systems reach the similar final temperature and demonstrate the benefit of the XXX. Authors are also recommended to discuss the temperature jump in initial 2-3 seconds for the no heatsink and the XXX case. The authors have presented a very good overview of the existing technology. The applicability of this technology, however, depends on availability of different XXXX. Authors are recommended to present a few exemplary XXXX¡¯s to show that this technology can be tuned for different applications requiring different turn on temperatures. The authors are requested to present a labeled cross section schematic of the displacement experiment i.e. figure 2 a. 5 mm droplet is sometimes too large for many MEMS applications. Also to achieve a better local thermal control the authors would like to design the heating array with as small a droplet as possible. Therefore the authors are recommended to discuss the effect of droplet miniaturization on the maximum displacement that can be achieved reversibly while considering the increasing effect of surface tension. The device schematic as shown has XXXX domes trapped in holes on copper plate. It is stated that the XXXX wets copper in its molten state. Then during operation of the device when the XXXX is in liquid phase how do the authors prevent the droplets to spread and wet the whole copper surface? Even if the wetting is slow, it will affect the long term operation of the device. |
50Â¥2012-12-01 10:18:11
userhung
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51Â¥2012-12-01 10:54:15
zhtear99
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zhtear99: »ØÌûÖö¥ 2012-12-05 19:48:11
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Ñо¿·½Ïò£º¼ÆËã»ú¸¨ÖúÒ©ÎïÉè¼Æ Ͷ¸åÔÓÖ¾Ãû³Æ£ºInternational Journal of Molecular Sciences Éó¸åÒâ¼û£º Reviewer 1# 1) This paper is well organized and of interest in the field, but some points must be clarified and discussed before it can be suitable of publication. 2) On page 3, line 113: "required empirical potential energy function" must be substituted with "force field parameters" since the term is wrong. A question on page 4 paragraph lines 118-121: How can the authors be sure that the most conformational analysis been made on each of these tow compounds? This point of course is crucial for a correct alignment and thus further analysis. 3) On page 7, another perplexity: How can the authors be sure that the crystallized water are indeed structural for the template protein too? Are there any experimental evidence? I suggest to repeat the docking calculations also in absence of water inside the cleft and tentatively compare the results obtained. This point of is crucial since all the discussion about the molecular interactions is linked to structural water playing a fundamental role in stabilization. 4) On page 11, figure 5: line 322-323: "tubes" instead of "ball and stick". Reviewer 1# Considering the situation that no X-ray structure of human proteasome exists, making good models of the enzyme as inhibitor-bound form help researchers conduct SAR study efficiently. The computational studies in this manuscript almost meet the demand. However, both compounds dealt with in this manuscript are covalent inhibitors. The reviewer would like the authors to state any good reason why only non-covalent interactions were considered in the calculations. Especially, TBA is believed to make reversible borate adduct form to display proteasome-inhibitory activity, and the bound structure should be more suitable to evaluate results from SAR studies on the compounds of this class. Recalculations is requested if needed. On the top of that, the following should be considered. Line 68: What abbreviation MM means (multiple myeloma) should be indicated. Line 101: "selected considered having a similar range" is grammatically incorrect. Line 227: change energy to energetically throuout: Usually, "big" is not used scientific articles like this. Change to large, bulky or other appropriate words. ¸öÈ˸ÐÏ룺Á½¸öÉó¸åÈ˸øµÄÒâ¼û¶¼ºÜºÃ¡£Á½Î»Éó¸åÈ˱ÈÎÒ»¹Ï¸ÐÄ£¬ÎÒû¼ì²é³öÀ´µÄÃ÷ÏÔ´íÎó±»ËûÃÇ¿´³öÀ´ÁË£¨‡åing£©£¬¶øÇÒµÚ¶þ¸öÉó¸åÈ˶ÔÎÒÃÇ×öµÄproteasomeºÜÁ˽⡣½²Ò»Ïµ±Ê±Í¶¸å·¢ÉúµÄС²åÇú°É¡£Õâ¼ÒÔÓÖ¾ÊÇÈÃͶ¸åÈË×Ô¼ºÍƼöÉó¸åÈ˵ġ£Ê¦½ã˵һ°ã¶¼ÔڹȸèѧÊõÀïËÑһϣ¬ÕÒ¼¸¸öQSAR·½ÃæµÄ´óÅ£¾Í¿ÉÒÔÁË¡£ÔÒòÓжþ£ºÒ»ÊÇ´óÅ£ºÜÀ÷º¦£¬¿ÉÒÔÌṩºÜºÃºÜרҵµÄÉó¸åÒâ¼û£»¶þÊÇ´óÅ£²»»áΪÄÑÔÛÃÇÕâЩСϺÃס£È»ºó£¬ÎÒ¾ÍÕâô×Å£¬ÕÒÁËÁ©´óÅ£µ±Éó¸åÈË¡£µ±Ê±´øÎÒ×öʵÑéµÄÀÏʦ֪µÀºó£¬ºÜ¹â»ð£¬ºÝºÝµØÑµÁËÎÒÒ»¶Ù¡£ÒòΪËû¸úÕâ¼ÒÔÓÖ¾µÄ¼¸¸öÉó¸åÈ˺ÜÊ죬Èç¹ûÎÒÍÆ¼öËûÈÏʶµÄÄǼ¸¸öÈ˵±Éó¸åÈË»á±È½Ï±£ÏÕ¡£Í¶ÍêÎÄÕºó£¬ÎÒã·ã·²»°²£¬µ£Ðı»¾Ü£¬Ò²¾õµÃ×Ô¼ºÌ«×ÔÒÔΪÊÇÁË£¬Ã»ÓÐÊÂÏÈÎÊÀÏʦ¡£×îºó£¬ÎÄÕÂÊÕµ½ÁËrevise¡£ÊÂʵ֤Ã÷£¬Ê¦½ãµÄ»°Ò²ÊÇÓеÀÀíµÄ¡£ËùÒÔËµÍÆ¼öÉó¸åÈ˵ÄÁ½ÖÖ·½Ê½ÆäʵӦ¸Ã¶¼¿ÉÐеġ£ PS£ºIJMSÊÇÊÕ·ÑÔÓÖ¾£¬IFÊÇ2µã¼¸°É¡£ÎÒ¹ÀÃþ×Å¿ÉÄÜÊÇÊշѵÄÔÒò£¬ËùÒÔ½ÓÊÜÂʱȽϸ߰ɡ£ [ Last edited by zhtear99 on 2012-12-1 at 14:50 ] |
52Â¥2012-12-01 14:41:40
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zhtear99: ½ð±Ò+15, ¸ÐлÀ´¸å~~~ 2012-12-02 12:37:16
zhtear99: »ØÌûÖö¥ 2012-12-02 12:37:18
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È¥ÄêͶ¸åµÄÉó¸åÒâ¼û£º Reviewer A: Comments for Reviewer's Assessment: The quality of English writing is very poor and the document must be revised by an native english speaking person. See my remarks in the enclosed file. Comments for the Authors: Interesting paper with a good patent review. The document requires major modifications and answers to my remarks as proposed in the enclosed file. Reviewer B: Comments for Reviewer's Assessment: The authors review approaches for addressing naphthenic acid corrosion, including usage of inhibitors, solvent extraction, chemical conversion, thermal treatment, and hydrotreatment. The review covers an important topic that will be of interest to the journals' readership and focuses upon patents between 2000 and 2011. Whilst the manuscript provides a summary of the methods employed, it does not provide much detail, making it harder for the reader to evaluate the advantages and disadvantages of each. The reviewer would recommend providing some additional description to strengthen the manuscript. |
53Â¥2012-12-02 11:38:32
lxg133298
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2Â¥2012-11-29 16:42:12
zhtear99
Ìú¸Ëľ³æ (ÖøÃûдÊÖ)
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3Â¥2012-11-29 16:47:48
lxg133298
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ר¼Ò¾Ñé: +201 - Ó¦Öú: 511 (²©Ê¿)
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4Â¥2012-11-29 16:55:23
zhtear99
Ìú¸Ëľ³æ (ÖøÃûдÊÖ)
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5Â¥2012-11-29 18:57:58
readytogo
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6Â¥2012-11-29 19:01:55
wg423
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7Â¥2012-11-29 19:02:29
wenxia503
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8Â¥2012-11-29 19:04:37
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10Â¥2012-11-29 19:18:18
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12Â¥2012-11-29 19:24:02
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lxg133298
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ר¼Ò¾Ñé: +201 - Ó¦Öú: 511 (²©Ê¿)
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14Â¥2012-11-29 19:24:37
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16Â¥2012-11-29 19:29:24
okitworks
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17Â¥2012-11-29 19:36:50
ÐÄÖÐÖ®»¨
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19Â¥2012-11-29 19:56:57
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20Â¥2012-11-29 19:57:49
zhtear99
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21Â¥2012-11-29 19:59:39
littleroad
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23Â¥2012-11-29 21:12:43
winter_north
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26Â¥2012-11-29 22:01:07
myIDname
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28Â¥2012-11-29 22:16:04
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29Â¥2012-11-29 22:43:42
lin_twins
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30Â¥2012-11-29 23:52:02
foxzy
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31Â¥2012-11-30 08:15:31
Tessatt
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36Â¥2012-11-30 08:54:56
37Â¥2012-11-30 08:59:46
seagrove
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38Â¥2012-11-30 09:11:51
laojiepaopao
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39Â¥2012-11-30 09:26:59
liziyu521
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43Â¥2012-11-30 15:36:14
zhtear99
Ìú¸Ëľ³æ (ÖøÃûдÊÖ)
- SFL-EPI: 1
- Ó¦Öú: 147 (¸ßÖÐÉú)
- ¹ó±ö: 0.662
- ½ð±Ò: 3343.9
- Ìû×Ó: 1869
- ÔÚÏß: 714.6Сʱ
- ³æºÅ: 1001108
44Â¥2012-11-30 15:44:26
yiriyoltu
ľ³æ (ÖøÃûдÊÖ)
- Ó¦Öú: 3 (Ó×¶ùÔ°)
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46Â¥2012-11-30 21:35:40
okitworks
ľ³æ (ÖøÃûдÊÖ)
- Ó¦Öú: 4 (Ó×¶ùÔ°)
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49Â¥2012-11-30 23:07:17
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mingfeng5179Â¥
2012-11-29 19:16
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zenglin199215Â¥
2012-11-29 19:27
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xunmeng198522Â¥
2012-11-29 21:02
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zyl1265024Â¥
2012-11-29 21:22
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zhtear99: ½ð±Ò+1, »¶ÓÀ´¸å¹þ~ 2012-11-29 23:12:16

seaskyzdw25Â¥
2012-11-29 21:40
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2012-11-30 08:22
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shhw200833Â¥
2012-11-30 08:24
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army88888834Â¥
2012-11-30 08:27
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likai113935Â¥
2012-11-30 08:36
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zhtear99: ½ð±Ò+1, »¶ÓÀ´¸å¹þ~ 2012-11-30 11:43:48


emuch41Â¥
2012-11-30 10:08
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appleboy47Â¥
2012-11-30 22:06
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su-b0848Â¥
2012-11-30 22:35
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