| 查看: 596 | 回复: 3 | ||
[求助]
求高人帮忙翻译一下 速度啊
|
|
The discriminative stimulus (DS) properties of d-amphetamine (AMP) are thought to be mediated by en- hanced release of catecholamines, which may involve neuro- nal calcium influx through voltage sensitive channels. The present study examined the influence of nimodipine, a calci- um channel blocker, on the DS properties of AMP. Rats (N=8) were trained to discriminate AMP (0.5 mg/kg, IP) from saline in a two-lever, food-reinforced, drug discrimina- tion paradigm. Nimodipine alone (2.0-5.6 mg/kg, IP) did not substitute for AMP. When given in combination with AMP, 2.0 mg/kg nimodipine increased by less than 2-fold the AMP dose necessary to induce AMP-appropriate re- sponses. Higher doses of nimodipine combined with AMP did not increase the magnitude of this effect. Nimodipine enhanced the effects of AMP on response rate. Haloperidol (0.125 mg/kg) increased by approximately 4-fold, whereas diazepam (0.5 or 1.0 mg/kg) and morphine (5.0 mg/kg) in- creased by approximately 2-fold the AMP dose necessary to induce AMP-appropriate responses. The interaction with AMP was associated with enhanced reduction of response rate in the tests with diazepam and morphine but not halo- peridol. These results suggest that nimodipine attenuates the DS properties of AMP, probably in a non-specific way, due to the ability of nimodipine itself to induce a discrimin- able internal state. |
回复此楼» 猜你喜欢
售SCI一区T0P文章，我:8O.55.1.O.54,科目全,可伽急
已经有17人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有21人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有21人回复
-
售SCI一区文章，我:8.O.55.1.O.54,科目齐全,可伽急
已经有8人回复
-
售SCI一区文章，我:8O5.5.1.O5.4,科目全,可伽急
已经有8人回复
-
售SCI一区T0P文章，我:8.O55.1.O.54,科目全,可十急
已经有8人回复
-
售SCI一区文章，我:8.O.55.1.O.54,科目齐全,可伽急
已经有6人回复
-
售SCI文章，我:8O5.5.1.O.54,科目齐全,可+急
已经有6人回复
-
售SCI文章，我:8O5.5.1.O.54,科目齐全,可+急
已经有15人回复
-
售SCI一区文章，我:8.O.55.1.O.54,科目齐全,可伽急
已经有14人回复
» 本主题相关价值贴推荐，对您同样有帮助:
- 我又来了！求高人帮忙翻译这段文章！谢谢啊！！！
已经有1人回复
- 跪求 英语高手帮忙翻译一下 急用啊 谢谢了
已经有2人回复
- 帮忙翻译一下摘要啊
已经有1人回复
- 帮忙翻译一下，谢谢
已经有5人回复
- 求 摘要 引言 结论翻译 （我已经自己翻译了一遍，希望高人帮忙修改一下）
已经有1人回复
- 求高人翻译以下句子，不懂里面的离心机的转速还用g
已经有4人回复
- 求高手帮忙 润色一下我的英语翻译
已经有2人回复
- 求高人帮忙翻译 汉译英
已经有3人回复
- 大家帮忙翻译一下，什么意思
已经有8人回复
- 求高手帮忙改一下英文摘要
已经有12人回复
- 哪位高手能帮忙翻译一下吗？谢谢
已经有2人回复
luwangxing
金虫 (正式写手)
- 应助: 28 (小学生)
- 金币: 2282.6
- 红花: 1
- 帖子: 370
- 在线: 134.6小时
- 虫号: 270178
- 注册: 2006-08-05
- 性别: GG
- 专业: 药剂学
2楼2012-05-23 14:07:46
风之魂灵zd
木虫 (正式写手)
- 应助: 6 (幼儿园)
- 金币: 3067.7
- 散金: 136
- 红花: 5
- 帖子: 859
- 在线: 163.1小时
- 虫号: 1408157
- 注册: 2011-09-19
- 性别: GG
- 专业: 海洋药物
3楼2012-07-04 10:23:44
4楼2012-11-05 16:22:18
50