24小时热门版块排行榜    

查看: 604  |  回复: 1

angel19860820

铁杆木虫 (著名写手)


[交流] AB审稿意见回复

analytical biochemistry因为做的太慢,只能投个差一点的杂志,1月底投,今天回复revise。意见如下
Dear **,

Your manuscript has been reviewed by individuals knowledgeable in this field. Although the reviewers were interested in the paper, questions were raised that are summarized in the reviewers' comments below.

Should you agree to revise the manuscript, please indicate the changes that have been made, and point-by-point responses to the reviewers' comments. In order to retain the original date of submission, a revised manuscript should be forwarded within two months of the date of this decision letter.

Please submit your revision online by logging on to the Analytical Biochemistry Elsevier Editorial System:
http://ees.elsevier.com/yabio/

Your username is: ******
If you need to retrieve password details, please go to: http://ees.elsevier.com/yabio/automail_query.asp

Your manuscript record is located in the "Submissions Needing Revision" menu.

When submitting your revised paper, please include a separate document called "Response to Reviews" detailing your responses to the comments of the reviewers. Most useful would be a copy in which the revisions are indicated directly on the manuscript, e.g. underlined or in color. Also include electronic source files for the text and figures that can be used for publication should the manuscript be accepted. These files should include the text, tables and figure legend in an editable format (MS Word preferred) and all figures saved individually as TIF or EPS files.


Reviewers' comments:


Reviewer #1: This manuscript reports **. The concept is worthy of investigation and some important experimental data has been provided on the operational performance of the sensor, including signal response and selectivity. However, there are significant problems with the authors' interpretation of some of the sensitivity and selectivity data and with a lack of clarity in some of their descriptions and conclusions. Specific points for the authors to address are detailed below.

5. Page 8 line 21 ". . . the height (27 +/- 2 nm) . . ." Over what surface area or over how many "islands" was this figure calculated? How indicative is it of the broader surface morphology over large areas?

7. Page 10 line 9 ". . . detection limit . . . 4 nM." This quoted detection limit is meaningless as you have not demonstrated actual detection of adenosine at anywhere near this concentration (your lowest non-blank standard is 200 nM). Based on the error in your blank point in Figure 3, three times its standard deviation would give a limit of detection of about 100-150 nM. Furthermore, this 4 nM figure does not agree with the 65 nM quoted in the abstract.


Reviewer #2:
4) Looking at Figure 3, it seems difficult to see how the limit of detection could be 4 nM. Especially since it seems that the lowest concentration tested looks to be about 200 nM. Perhaps the authors could show an inset to the figure with concentrations up to only 100 nM.
其他问的问题都是咬文嚼字的小问题,就这几个问题比较大,不好回答,关于这个检测线,我是当时发现自己算错了,重新算过结果有些地方没有改过来,这个在回复的时候可以直接这样说么,还是有其他比较容易让审稿人接受的说法。他们说的是对的,是我当时没有搞好
关于用AFM观察表面形貌的,他问的应该是说我看的只是一个片子的一小部分,不能代表整个片子的情况,我是不是要用软件计算出整个片子上修饰物的量是多少才可以说明这个问题?
谢谢
回复此楼

» 猜你喜欢

» 本主题相关价值贴推荐,对您同样有帮助:

» 抢金币啦!回帖就可以得到:

查看全部散金贴

已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

angel19860820

铁杆木虫 (著名写手)


某人回复么?AFM可以计算表面修饰量么
2楼2013-02-26 21:24:12
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 angel19860820 的主题更新
普通表情 高级回复 (可上传附件)
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 材料与化工考研调剂 +7 孅華 2026-03-22 7/350 2026-03-24 21:04 by greychen00
[考研] 086003食品工程求调剂 +5 淼淼111 2026-03-24 5/250 2026-03-24 20:53 by lailaisimei
[考研] 化工专硕求调剂 +3 question挽风 2026-03-24 3/150 2026-03-24 18:48 by jhhcooi
[考研] 一志愿华东理工大学081700,初试分数271 +5 kotoko_ik 2026-03-23 6/300 2026-03-24 10:29 by 学术搬砖er
[考研] 一志愿吉大化学322求调剂 +4 17501029541 2026-03-23 6/300 2026-03-24 10:21 by 戴围脖的小蚊子
[考研] 284求调剂 +10 Zhao anqi 2026-03-22 10/500 2026-03-24 00:08 by Equinoxhua
[考研] 求材料,环境专业调剂 +3 18567500178 2026-03-18 3/150 2026-03-23 23:50 by 热情沙漠
[考研] 269求调剂 +4 我想读研11 2026-03-23 4/200 2026-03-23 21:25 by pswait
[考研] 315分,诚求调剂,材料与化工085600 +3 13756423260 2026-03-22 3/150 2026-03-22 20:11 by edmund7
[考研] 289求调剂 +7 怀瑾握瑜l 2026-03-20 7/350 2026-03-22 15:57 by ColorlessPI
[考研] 269专硕求调剂 +6 金恩贝 2026-03-21 6/300 2026-03-22 14:31 by ColorlessPI
[考研] 285求调剂 +6 ytter 2026-03-22 6/300 2026-03-22 12:09 by 星空星月
[考研] 材料学硕333求调剂 +3 北道巷 2026-03-18 3/150 2026-03-21 18:17 by 学员8dgXkO
[考研] 311求调剂 +3 勇敢的小吴 2026-03-20 3/150 2026-03-21 17:40 by ColorlessPI
[考研] 一志愿重庆大学085700资源与环境总分308求调剂 +7 墨墨漠 2026-03-20 7/350 2026-03-21 16:36 by barlinike
[考研] 一志愿重庆大学085700资源与环境专硕,总分308求调剂 +3 墨墨漠 2026-03-18 3/150 2026-03-21 00:39 by JourneyLucky
[考研] 一志愿南昌大学,327分,材料与化工085600 +9 Ncdx123456 2026-03-19 9/450 2026-03-20 23:41 by lovewei0727
[考研] 求调剂 +3 @taotao 2026-03-20 3/150 2026-03-20 19:35 by JourneyLucky
[考研] 一志愿南理工085701环境302求调剂院校 +3 葵梓卫队 2026-03-20 3/150 2026-03-20 19:28 by zhukairuo
[考研] 085410人工智能专硕317求调剂(0854都可以) +4 xbxudjdn 2026-03-18 4/200 2026-03-20 09:07 by 不168
信息提示
请填处理意见