24小时热门版块排行榜

返回列表

米西222

新虫 (初入文坛)

应助: 0 (幼儿园)
金币: 19
散金: 1
帖子: 12
在线: 35.5小时
虫号: 1412256
注册: 2011-09-22
专业: 生物化学

[求助] 关于Dna transposon

我是初学生物的新手最近看英文有一段关于Dna transposon 的解释看不懂求高手解释下：cut and paste 型的转座怎么会有duplication呢？（最好简要说下下面文字重点）不甚感激~~~~
Class II (DNA transposons): By contrast, the cut-and-paste transposition mechanisms of class II transposons do not involve an RNA intermediate. These transpositions are catalyzed by various types of transposase enzymes. Some transposases can bind non-specifically to any target site, while others bind to specific sequence targets. The transposase makes a staggered cut at the target site producing sticky ends, cuts out the transposon and ligates it into the target site. A DNA polymerase fills in the resulting gaps from the sticky ends and DNA ligase closes the sugar-phosphate backbone. This results in target site duplication and the insertion sites of DNA transposons may be identified by short direct repeats (a staggered cut in the target DNA filled by DNA polymerase) followed by inverted repeats (which are important for the transposon excision by transposase). The duplications at the target site can result in gene duplication, which plays an important role in evolution[4]:284.

回复此楼

» 猜你喜欢

1楼 2011-10-13 11:08:28

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

智能机器人

Robot (super robot)

我们都爱小木虫

找到一些相关的精华帖子，希望有用哦~

点击这里搜索更多相关资源

科研从小木虫开始，人人为我，我为人人

相关版块跳转我要订阅楼主米西222 的主题更新

返回列表