| 查看: 558 | 回复: 2 | |||
| 【奖励】 本帖被评价2次,作者keven7928增加金币 1.6 个 | |||
[资源]
Chem Soc Rev上的Conformational changes of non-B DNA
|
|||
|
Conformational changes of non-B DNA In contrast to B-DNA that has a right-handed double helical structure with Watson–Crick base pairing under the ordinary physiological conditions, repetitive DNA sequences under certain conditions have the potential to fold into non-B DNA structures such as hairpin, triplex, cruciform, left-handed Z-form, tetraplex, A-motif, etc. Since the non-B DNA-forming sequences induce the genetic instability and consequently can cause human diseases, the molecular mechanism for their genetic instability has been extensively investigated. On the contrary, non-B DNA can be widely used for application in biotechnology because many DNA breakage hotspots are mapped in or near the sequences that have the potential to adopt non-B DNA structures. In addition, they are regarded as a fascinating material for the nanotechnology using non-B DNAs because they do not produce any toxic byproducts and are robust enough for the repetitive working cycle. This being the case, an understanding on the mechanism and dynamics of their structural changes is important. In this critical review, we describe the latest studies on the conformational dynamics of non-B DNAs, with a focus on G-quadruplex, i-motif, Z-DNA, A-motif, hairpin and triplex (189 references). |
» 收录本帖的淘帖专辑推荐
国外专业电子书 |
» 猜你喜欢
2019年青年基金涵评意见,大家看看几个A,几个B?
已经有5人回复
职称评审,求友友推荐见刊最快的期刊
已经有4人回复
奇怪,两个人的filecode固定段从头到尾一模一样
已经有10人回复
应该是93bebmhtak前后十一个字符比较关键
已经有30人回复
综述论文作为代表作会不会影响评审专家的印象分?
已经有13人回复
是这周出结果还是下周出结果?
已经有3人回复
小木虫上这么多卖论文的,真有人买论文么?感觉没必要啊
已经有9人回复
有时候,自然基金真的不能太认真 (我的申报经验)
已经有4人回复
帮忙看看fileCode
已经有13人回复
为什么网上很多人说本周 12号出结果
已经有7人回复
» 本主题相关价值贴推荐,对您同样有帮助:
用DNAmarker制备噬菌体
已经有4人回复
酶切质粒DNA选什么材料比较好?
已经有5人回复
染色剂的浓度对DNA电泳亮度有多大影响
已经有5人回复
请问大家分析抗性基因(或差异表达基因等相关的)的方法有哪些?比如DNA微阵列。。。
已经有10人回复
新提的质粒DNA,关于浓度和纯度虫友们发表一些看法吧
已经有32人回复
Chem Soc Rev综述:Au纳米颗粒用于生化检测
已经有174人回复
Chem Soc Rev最新综述:纳米材料毒性
已经有304人回复
Chem. Soc. Rev.:包覆无机纳米材料对细胞毒性的影响
已经有363人回复
Chem. Soc. Rev最新综述,about 银量子点及其生物应用
已经有183人回复
endnote X5 版中从web of science 中自动导入文献,出现filter怎么办
已经有5人回复
ChemComm投稿求助
已经有22人回复
Chem Soc Rev:一篇机械化学法综述
已经有309人回复
包信和院士Acc Chem Res,讨论了碳纳米管限域的催化剂
已经有168人回复
【求助/交流】怎么做都提不出DNA,请高手帮一下忙喽!!!!
已经有52人回复
【求助/交流】求助-苯酚氯仿纯化DNA方法
已经有12人回复
2楼2011-10-10 13:31:56
3楼2011-11-03 16:11:58










回复此楼