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ziyunpy

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专业: 畜牧学

[交流] 【求助/交流】mRNA和 exon是什么关系已有3人参与

mRNA和 exon是什么关系
exon1+exon2+exon3+......=mRNA吗？
还是exon1+exon2+exon3+......=CDS区？
有点糊涂了，请教大家，谢谢！

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努力不等以成功

1楼 2010-06-22 16:34:18

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

ziyunpy

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专业: 畜牧学

这个序列什么意思

AUTHORS Koltes,J.E., Mishra,B.P., Kumar,D., Kataria,R.S., Totir,L.R.,
         Fernando,R.L., Cobbold,R., Steffen,D., Coppieters,W., Georges,M.
         and Reecy,J.M.
  TITLE    A nonsense mutation in cGMP-dependent type II protein kinase
         (PRKG2) causes dwarfism in American Angus cattle
  JOURNAL Proc. Natl. Acad. Sci. U.S.A. 106 (46), 19250-19255 (2009)
PUBMED 19887637
REFERENCE 2  (bases 1 to 2450)
  AUTHORS Koltes,J.E., Mishra,B.P., Kumar,D., Kataria,R.S., Totir,L.R.,
         Fernando,R.L., Cobbold,R., Steffen,D., Coppieters,W., Georges,M.
         and Reecy,J.M.
  TITLE    Direct Submission
  JOURNAL Submitted (16-JUL-2009) Department of Animal Science, Iowa State
         University, 2255 Kildee Hall, Ames, IA 50011-3150, USA
FEATURES          Location/Qualifiers
   source       1..2450
                  /organism="Bos taurus"
                  /mol_type="genomic DNA"
                  /db_xref="taxon:9913"
                  /chromosome="6"
                  /note="breed: Angus"
   gene          1..2450
                  /gene="FGF5"
   misc_feature 1..113
                  /gene="FGF5"
                  /note="contains promoter region and 5' UTR"
   mRNA          <114..>478
                  /gene="FGF5"
                  /product="fibroblast growth factor 5"
   CDS          114..>478
                  /gene="FGF5"
                  /note="coding region disrupted by a sequencing gap"
                  /codon_start=1
                  /product="fibroblast growth factor 5"
                  /protein_id="ADE42981.1"
                  /db_xref="GI:293337385"
                  /translation="MSLSFLLLLFLSHLILSAWAQGEKRLAPKGQPGPAATERNPGGA
                  SSRRSSSSTATSSSSPASSSSAASRGGPGSSLEQSSFQWSPSGRRTGSLYCRVGIGFH
                  LQIYPDGKVNGSHEANMLS"
   gap          624..723
                  /estimated_length=unknown
   mRNA          <731..>1078
                  /gene="FGF5"
                  /product="fibroblast growth factor 5"
   CDS          <731..1078
                  /gene="FGF5"
                  /note="coding region disrupted by a sequencing gap"
                  /codon_start=1
                  /product="fibroblast growth factor 5"
                  /protein_id="ADE42982.1"
                  /db_xref="GI:293337386"
                  /translation="AKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGK
                  AKRGCSPRVKPQHVSTHFLPRFKQLEQPELSFTVTVPEKKKPPNPVKPKVPLSAPRRS
                  PNTVKYRLKFRFG"
   gap          1345..1444
                  /estimated_length=unknown
ORIGIN
      1 atgtccaccc ggtgcggcga ggggggcagc gccagaggca cgcagccgcg caggggctac
   61 gaagcccaga accaaccctg caagatgcac ttaggacccc cgcggctgga agcatgagct
   121 tgtccttcct cctcctcctc ttcctcagcc acctgatcct cagcgcctgg gctcaagggg
   181 agaagcgcct cgcacccaaa gggcagcccg gacctgctgc caccgagagg aacccgggag
   241 gcgccagcag ccgccggagc agcagtagca ccgcgacttc ctcttcttcc cctgcctcct
   301 cctcctccgc ggcttctcgg ggcggcccag gaagcagctt ggagcagagc agcttccagt
   361 ggagcccctc ggggcgccgg accggcagcc tctactgcag agtgggcatc ggtttccatc
   421 tgcagatcta cccggatggc aaagtcaacg gctcccacga agccaatatg ttaagtaagt
   481 tgcttgctst cctccaaaac ctgtcttgag cgggtggcgg gagcatcgag agggaccgcc
   541 ggttattccc caggctgtaa gcgcaccttc cggagcctgg gccactggga tcccagccgg
   601 ccctcgaaac agccgggttg ggt
      [gap 100 bp] Expand Ns
   724 cctctag gccaaattta cagatgactg caagttcagg gagcgatttc aagaaaacag
   781 ctataatacc tatgcctctg cgatacacag aactgaaaag acggggcggg agtggtacgt
   841 ggccctgaac aagaggggga aggctaaacg gggctgtagc ccccgggtta aacctcagca
   901 cgtctctacc cactttctgc caagattcaa gcaattggag cagccggaac tttctttcac
   961 agttactgtt cccgaaaaga aaaagccacc taatcctgtc aagccaaagg ttcccctttc
   1021 cgcacctcgg agaagtccta acaccgtgaa atacagactc aagtttcgct ttggttaaga
   1081 cttactttgg ttttgtgaga aaccatgrag tctcctcagg agtttctgca gctgtcctca
   1141 gtgctctgaa gacaacttct tggacacagc ttcagctata tactacactg tattgaagtc
   1201 aggtcatttg tttcagcttg actgaaacaa aaatgttttc tgatagtaac tgaactggaa
   1261 ttctttgtac caatataggg agttcacgac gacataaagc cttttgcttt atgcttggtg
   1321 catacaggga ttcttttttg gaaa
      [gap 100 bp] Expand Ns
   1445    tttttc tgacttttac agatcaacct gaagaaaaca tacatgatac atttttattt
   1501 ttggtttcca aagaatattt tgatggagat aaaagtattt tattagattt ttttttaaag
   1561 tacctctgca ttgagcatat tttcttactt ttattatttc taattgataa gatatgaaac
   1621 aaccatttta atgcagttta tgaattataa atatgtttat agaccatttt taacatgtgg
   1681 atttcttttt cattgttctc aktcattgca cttttaattt ttattatgat tgtttttcta
   1741 ccatacctca gatcatgtaa gtttaatttt acatcttaaa atgtttaaat tctcttcaac
   1801 agcactaaag sctcagcttg tgtttgtgtg tgtgtgtgag tgtgtgtaaa ttcatgattt
   1861 tatatatgga atcctgtctc tgtggtggct gggctataat gggttagaag taaggagaaa
   1921 acgtaaggaa tttttggtgg aattaaaagt tgaggcaagg aaaagaatta gaggttcaag
   1981 tgcactgatt ttgcagtgtt tattgatagc taattctacy ttgccttcac ttcccatttt
   2041 atctaccccc tgccctcatt ctttaaagct ggagaaatac attttattct gtccatcaag
   2101 catagactat gaaaccagag tgcttaaaat acctcttcta tgaccttctg ctatctccac
   2161 tgtatagatc cacagggagc aacccattta gtggaaaaac ayggagaacc gaaggagatg
   2221 aatcatgtaa cagttatcca tgtcaagtcc cattatctaa aatattatta ctcaaacact
   2281 ctttgagttt cctatcctaa aggtaaacac ctcagtgaat agatctgccc ttttataagg
   2341 aaaatttcta tgtatatttt taaatagttg gctatgtgac atgggaaact taatctgatg
   2401 agytgaaaat ggcacttaaa tgtcaaccca aatactgaat gtttggtata