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zhang8211jie

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专业: 生物化学与分子生物学

[交流] 【求助】求助一句免疫学文献内容的翻译已有3人参与

The protein microarrays were probed with human sera from one of four groups which differed in immune status: sterile immunity or no immunity against experimental challenge following vaccination with radiation-attenuated Pf sporozoites, partial immunity acquired by natural exposure, and no previous exposure to Pf.
本人英语知识有限，词句理解费劲，有谁可以帮我翻译一下此句话，谢谢！

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1楼 2010-05-01 12:46:23

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

resurgam

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zhang8211jie(金币+1): 2010-06-24 16:09:26
zhang8211jie(金币+1): 2010-06-24 16:09:40

蛋白芯片被4组人类血清中的一组检测，这4组人有着不同的免疫状态，分别是：无菌免疫、接种经辐射削弱的Pf孢子体无免疫、自然暴露后获得的部分免疫、之前从未与Pf接触。

PS：有关什么是protein microarray，可以参看：http://en.wikipedia.org/wiki/Protein_microarray

A protein microarray, sometimes referred to as a protein binding microarray, provides a multiplex approach to identify protein–protein interactions, to identify the substrates of protein kinases, to identify transcription factor protein-activation, or to identify the targets of biologically active small molecules. The array is a piece of glass on which different molecules of protein or specific DNA binding sequences (as capture probes for the proteins) have been affixed at separate locations in an ordered manner thus forming a microscopic array. The most common protein microarray is the antibody microarray, where antibodies are spotted onto the protein chip and are used as capture molecules to detect proteins from cell lysate solutions.

Related microarray technologies also include DNA microarrays, cellular microarrays, antibody microarrays, tissue microarrays and chemical compound microarrays.