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[求助]
请帮我查一下文章SCI收录号，谢谢！
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| 求助，哪位能进web of science的，请帮我查一篇文章是否被SCI收录？Expression and prognostic significance of p21-activated kinase 6 in hepatocellular carcinoma.J Surg Res. 2014 Jun 1;189(1):81-8. doi: 10.1016/j.jss.2014.01.049. Epub 2014 Jan 29. |
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baiyuefei
版主 (文学泰斗)
风雪
- LS-EPI: 1647
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【答案】应助回帖
感谢参与，应助指数 +1
oven1986: 检索EPI+1, 感谢应助！ 2014-05-28 22:22:04
oven1986: 检索EPI+1, 感谢应助！ 2014-05-28 22:22:04
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http://apps.webofknowledge.com/f ... age=1&doc=1 Expression and prognostic significance of p21-activated kinase 6 in hepatocellular carcinoma 作者:Chen, HW (Chen, Hongwei)[ 1 ] ; Miao, JL (Miao, Jinlin)[ 2 ] ; Li, HC (Li, Hongchen)[ 1 ] ; Wang, CH (Wang, Chunhua)[ 1 ] ; Li, JL (Li, Junliang)[ 1 ] ; Zhu, Y (Zhu, Yong)[ 1 ] ; Wang, JX (Wang, Jianxin)[ 1 ] ; Wu, X (Wu, Xia)[ 1 ] ; Qiao, HY (Qiao, Hongying)[ 1 ] JOURNAL OF SURGICAL RESEARCH 卷: 189 期: 1 页: 81-88 DOI: 10.1016/j.jss.2014.01.049 出版年: JUN 2014 查看期刊信息 摘要 Background: p21-activated protein kinase (PAK) 6 is a serine-threonine kinase belonging to the PAK family. Previous studies have indicated that abnormal expressions of PAK1, PAK2, and PAK5 played critical roles in hepatocellular carcinoma (HCC). Recent studies suggested that deregulation of PAK6 expression played an important role in oncogenesis. To explore the potential roles of PAK6 in HCC, expression of PAK6 was detected in human HCC specimens. Methods: Immunohistochemistry and Western blot analysis were performed for PAK6 in 121 HCC samples. The data were correlated with clinicopathologic features. The univariate and multivariate survival analyses were also performed to determine their clinical prognostic significance. Results: PAK6 was overexpressed in HCC as compared with the adjacent noncancerous liver tissues. High expression of PAK6 was associated with Edmondson-Steiner grade (P = 0.006) and number of tumor nodules (P < 0.001), and PAK6 was positively correlated with proliferation marker Ki-67 (P < 0.01). Univariate analysis suggested that PAK6 expression was associated with poor prognosis (P < 0.001). Multivariate analysis indicated that PAK6 and Ki-67 protein expressions were independent prognostic markers for HCC (P = 0.0245 and 0.0331, respectively). Conclusions: Our results suggest that PAK6 overexpression is involved in the pathogenesis of HCC; it may be an independent poor prognostic factor for HCC. (C) 2014 Elsevier Inc. All rights reserved. 关键词 作者关键词:Hepatocellular carcinoma; PAK6; Ki-67; Proliferation KeyWords Plus:BREAST-CANCER CELLS; COLORECTAL-CANCER; PROTEIN-KINASE; MIGRATION; PAK6; PHOSPHORYLATION; PATHOGENESIS; PROGRESSION; METASTASIS; INVASION 作者信息 通讯作者地址: Chen, HW (通讯作者) First Hosp Qinhuangdao, Dept Clin Lab, 258 Wenhua Rd, Qinhuangdao 066000, Peoples R China. 地址: [ 1 ] First Hosp Qinhuangdao, Dept Clin Lab, Qinhuangdao 066000, Peoples R China [ 2 ] Fourth Peoples Hosp Taizhou, Dept Magnet Resonance Imaging, Taizhou, Peoples R China 电子邮件地址:hongweichen0306@outlook.com 基金资助致谢 基金资助机构 授权号 Qinhuangdao Foundation for Development of Science and Technology, China 201302A073 查看基金资助信息 出版商 ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA 类别 / 分类 研究方向:Surgery Web of Science 类别:Surgery 文献信息 文献类型:Article 语种:English 入藏号: WOS:000334850900011 ISSN: 0022-4804 电子 ISSN: 1095-8673 期刊信息 Impact Factor (影响因子): Journal Citation Reports® 其他信息 IDS 号: AF6UU Web of Science 核心合集中的 "引用的参考文献": 43 Web of Science 核心合集中的 "被引频次": 0 |
2楼2014-05-27 16:48:08
baiyuefei
版主 (文学泰斗)
风雪
- LS-EPI: 1647
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- 帖子: 69384
- 在线: 13283.5小时
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- 专业: 合成药物化学
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3楼2014-05-27 16:48:23