±±¾©Ê¯ÓÍ»¯¹¤Ñ§Ôº2026ÄêÑо¿ÉúÕÐÉú½ÓÊÕµ÷¼Á¹«¸æ
²é¿´: 2678  |  »Ø¸´: 4
µ±Ç°Ö»ÏÔʾÂú×ãÖ¸¶¨Ìõ¼þµÄ»ØÌû£¬µã»÷ÕâÀï²é¿´±¾»°ÌâµÄËùÓлØÌû

titankop

гæ (³õÈëÎÄ̳)

[½»Á÷] Ͷ¸åInternational Journal of Cancer±»¾ÜÁË£¬ÀϰåÒªÎÒargue£¬´ó¼Ò¿´¿´¿ÉÄÜÂ𣿠ÒÑÓÐ3È˲ÎÓë

ÎÄÕ±»¾ÜÁË£¬µ«ÊÇ¿´ÁËÏÂÆÀÂÛ£¬ÀϰåÒªÎÒargue£¬´ó¼Ò˵ÎÒÊǰ´ÕÕÒâ¼ûÐÞ¸ÄÁËÔÙargue»¹ÊÇÏÈargueÒªÇóÐ޸ģ¬ÔÙ²¹Êý¾Ý£¬argueÏ£Íû´óÂð£¿
ÒÔÏÂÊÇÉó¸åÒâ¼û£º
05-Mar-2014
Re: IJC-14-0243

Dear XXX:

Thank you for submitting your manuscript XXX to the International Journal of Cancer. Our reviewing process has now been completed, and your paper has been reviewed by three outside referees and studied by the Editors. After careful consideration, we regret to say that we find your manuscript unsuited for publication in the IJC. Our decision is based on the lower priority of the work in light of current competition for publication and our stringent criteria. You can view the reviewer comments below.

We do hope that you find the reviews helpful and remain sorry that our answer cannot be a positive one. Thank you for your interest in IJC. We hope that this decision will not dissuade you from submitting your work again in the future.

Yours sincerely,
Prof. Peter Lichter
Editor-in-Chief
International Journal of Cancer

Reviewer: 1

Comments to Author
The manuscript by XXX shows that XXXXX£¨ÎÒµÄÎÄÕÂÄÚÈݸÅÀ¨£©and therefore we see significant bystander effect. The data are robust and clear.

Major criticisms:
In my opinion, this study lacks novelty,given that a recently published paper by the same group addressed similar questions except liposomes part. £¨µ«ÊÇÎÒÁ½ÆªÎÄÕ¿´Ï´´ÐµãÍêÈ«²»Ò»Ñù°¡£¬ÕâÆªÊÇÉÏÆªµÄÉîÈ뻯£¬Ð§¹û¼ÓÇ¿ÁË£¬¶øÇÒÑо¿ÁË»úÖÆ,ÍêÈ«²»Ò»Ñù°¡£¬Ö®Ç°ÊÇÒ»¸öÔØÌå°ÐÏòÏÖÔÚÊÇË«°ÐÏò°¡£©¡£

Reviewer: 2


Comments to Author
The manuscript entitled XXX demonstrates XXX£¨ÎÒµÄÎÄÕÂÄÚÈÝ)¡£ The authors showed XXX£¨ÎÄÕµĴ´ÐµãºÍ½áÂÛ£¬µÚ¶þ¸öÆÀί¶¼¿´¶®ÕâÆªµÄ´´ÐÂÒâÒåÁË£©¡£
Although there are a few points that need to be clarified, the manuscript is well written:

1. Page 5, line 31:XXX£¨ËµÎÒÒ»¸ö¸ÅÄî²»¹»È«£©. Please consider adding the following citation to the text (one example of many): XXX(ÐèÒªÌí¼ÓµÄÎÄÏ×£©¡£
2. Page 5, line 41: XXX £¨Ò²ÊÇÒ»¸ö¸ÅÄîÐèÒª²¹³ä£©. Relevant reference can be:  XXX(ÐèÒªÌí¼ÓµÄÎÄÏ×£©
3. Page 7, line 51-57:XXX (ÎÒµÄÒ»¸ö½á¹û£©. Can the authors clarify the reason for not choosing the same administration route for XXX£¨Ò»¸öÐèÒª½âÊÍΪʲôʵÑéÕâô×öµÄµØ·½£©?
4. Efficacy study: Did the authors perform an in vivo survival study XXX(ÒªÇó²¹³äÒ»¸öÌåÄÚʵÑ飩
5. Page 18, line 54: "XXX¡°£¨ÎÒµÄÒ»¸ö½áÂÛ£©. Please mention the reason for it: large-sized particles. £¨¾ÍÊÇÎÄ×ָĶ¯Ï£©
6. Did the authors perform long-term storage stability analysis for the liposomal formulation £¨¾ÍÊDz¹³äÒ»¸öÎȶ¨ÐÔʵÑ飬Æäʵ×öÁËÖ»ÊÇû·ÅÉÏÈ¥£¬²»³ÉÎÊÌ⣩?


Reviewer: 3

Comments to Author
The authors looked at the therapeutic efficacy of XXXX£¨ÎÄÕÂÄÚÈÝ£©. The study demonstrates significant  XXX (ʵÑé½á¹û£©, and showed potential for safe and efficient gene therapy £¨´´ÐµãºÍÁÙ´²Ó¦Óã©. Following concerns need to be addressed:
1. Figure 2D versus 2E: The authors used XXX £¨ÈÃÎÒ²¹³äÒ»¸ö¶Ô¶¾ÐÔÊý¾ÝµÄ½âÊÍ˵Ã÷£©
2. Figure 4E: The high apoptosis with XXX £¨ÎÒµÄÒ©Î would be better reflected by quantitative data. Please provide the comparative data with ratio of apoptotic cells in a given region with each formulation.
3. Figure 4F: The goal of XXX £¨ÎÒµÄÑо¿Ä¿µÄ£©. The integrity of the normal lung tissue would be best understood if a histologic score with each formulation is provided.
4. Many errors occur throughout the manuscript which need revision. £¨¿´À´Òâ˼ÊÇÐèÒªÓïÑÔÉϵĸĽø£¬»¹ÊÇÓÐÓï·¨´íÎó£©

Thanks.

[ ·¢×ÔÊÖ»ú°æ http://muchong.com/3g ]

[ Last edited by titankop on 2014-3-7 at 14:56 ]
»Ø¸´´ËÂ¥

» ²ÂÄãϲ»¶

» ±¾Ö÷ÌâÏà¹Ø¼ÛÖµÌùÍÆ¼ö£¬¶ÔÄúͬÑùÓаïÖú:

ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

СܰÔÂ

½ð³æ (ÖøÃûдÊÖ)

¡ï
Сľ³æ: ½ð±Ò+0.5, ¸ø¸öºì°ü£¬Ð»Ð»»ØÌû
ÇëÎÊÄúͶ³É¹¦ÁËÂð£¬ÏëÎÊÎÊÕâ¸öÔÓÖ¾¸ñʽ
4Â¥2018-03-20 15:47:24
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
²é¿´È«²¿ 5 ¸ö»Ø´ð

kingki

ÖÁ×ðľ³æ (ÖªÃû×÷¼Ò)

¡ï
Сľ³æ: ½ð±Ò+0.5, ¸ø¸öºì°ü£¬Ð»Ð»»ØÌû
¸ÄͶ°É£¬¸ß·ÖÔÓÖ¾»ù±¾ÉÏûÓÐÏ£Íû
·ÉÔ½ÎÞÏÞ
2Â¥2014-03-07 14:40:59
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

titankop

гæ (³õÈëÎÄ̳)

ÒýÓûØÌû:
2Â¥: Originally posted by kingki at 2014-03-07 14:40:59
¸ÄͶ°É£¬¸ß·ÖÔÓÖ¾»ù±¾ÉÏûÓÐÏ£Íû

¶÷£¬ºÍÀϰåÔÙȥ˵˵£¬Òª²»¸ÄͶӢ¹úÖ×ÁöÄǸö£¬¸Ð¾õÆÀ¼Û²»ÍêÈ«¸ºÃ棬»ù±¾¶¼ÕýÃæ°¡£¬½á¹û´óÐÞ¶¼²»¸øÒ»¸ö.
¸Ð¾õºóÁ½¸öÉó¸åÈ˸øµÄÒâ¼û¶¼ÊÇÐ޻ذ¡£¬µÚÒ»¸öҲ˵ÁËrobust and clear¡£¶ø´´ÐÂÐÔÃ÷ÏÔµÚÒ»¸öû¿´¶®£¬ºóÁ½¸ö¶¼¿´³öÀ´ÁË

[ Last edited by titankop on 2014-3-7 at 14:47 ]
3Â¥2014-03-07 14:42:51
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

¹ú¼Ê¿ÆÑ§±à¼­

Ìú¸Ëľ³æ (ÖªÃû×÷¼Ò)


¡ï
Сľ³æ: ½ð±Ò+0.5, ¸ø¸öºì°ü£¬Ð»Ð»»ØÌû
Á½¸ö´óÐÞ£¬Ò»¸öreject£¬argueÒ²»ù±¾Ã»Ï·¡£

·¢×ÔСľ³æIOS¿Í»§¶Ë
5Â¥2018-03-21 10:21:15
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] ÉúÎïѧ303Çóµ÷¼Á£¬Ò»Ö¾Ô¸»ªÖÐũ΢ÉúÎÁù¼¶Òѹý£¬ÓпÆÑÐÓÐÎÄÕ£¬µ³Ô± +4 .fairy.. 2026-03-29 5/250 2026-04-05 10:04 by zhuwenxu
[¿¼ÑÐ] Ò»Ö¾Ô¸ÄϺ½£¬ÊýһӢһѧ˶317Çóµ÷¼Á£¡£¡ +3 Acaciad 2026-04-04 3/150 2026-04-04 22:29 by lbsjt
[¿¼ÑÐ] 292·Ö£¬²ÄÁÏÓ뻯¹¤£¬ÉêÇëµ÷¼Á +22 ³ÌÇçÖ® 2026-04-01 26/1300 2026-04-04 22:03 by hemengdong
[¿¼ÑÐ] »·¾³285·Ö£¬¹ýÁù¼¶£¬Çóµ÷¼Á +10 xhr12 2026-04-02 10/500 2026-04-04 21:53 by bn53987
[¿¼ÑÐ] 081200-11408-276ѧ˶Çóµ÷¼Á +5 ´Þwj 2026-03-31 5/250 2026-04-04 19:45 by 1753564080
[¿¼ÑÐ] 334Çóµ÷¼Á +8 ÔøÑöÖ® 2026-04-03 8/400 2026-04-04 11:16 by w_xuqing
[¿¼ÑÐ] 294Çóµ÷¼Á +6 Grey_Ey 2026-04-03 6/300 2026-04-03 20:46 by ÐÀϲ777
[¿¼ÑÐ] ÊÞÒ½µ÷¼Á +3 wh119216 2026-04-02 3/150 2026-04-03 19:34 by zrongyan
[¿¼ÑÐ] Ò»Ö¾Ô¸ÉúÎïÓëÒ½Ò©£¬296·Ö£¬Çóµ÷¼Á +8 66¹ 2026-04-03 9/450 2026-04-03 14:22 by »¯Ñ§»¯¹¤Ë¶Ê¿ÕÐÉ
[¿¼ÑÐ] 319Çóµ÷¼Á +18 Ì«ÈÝÒ×1018 2026-04-01 18/900 2026-04-03 11:18 by linyelide
[¿¼ÑÐ] ר˶ 351 086100 Ò²ÊÇ¿¼µÄ²Ä¿Æ»ù ±¾¿ÆÒ²ÊDzÄÁÏ +8 202451007219 2026-04-02 8/400 2026-04-03 09:50 by À¶ÔÆË¼Óê
[¿¼ÑÐ] ²ÄÁϵ÷¼Á +4 Ò»ÑùYWY 2026-04-03 4/200 2026-04-03 09:48 by À¶ÔÆË¼Óê
[¿¼ÑÐ] 309Çóµ÷¼Á +14 ´ô¹½²»ÊÇ´÷·ò 2026-04-02 14/700 2026-04-03 09:42 by À¶ÔÆË¼Óê
[¿¼ÑÐ] ÖØÇì´óѧ²ÄÁÏÓ뻯¹¤085600£¬³õÊÔ370+£¬ÇóÇóµ÷¼Á½¨Òé +8 shzhou_ 2026-04-01 9/450 2026-04-03 09:31 by À¶ÔÆË¼Óê
[¿¼ÑÐ] 372·Ö²ÄÁÏÓ뻯¹¤£¨085600£©Ò»Ö¾Ô¸ºþÄÏ´óѧÇóµ÷¼Á +5 À¶¼ãƬ 2026-04-02 6/300 2026-04-02 21:37 by dongzh2009
[¿¼ÑÐ] ²ÄÁÏ0856 Ó¢Ò»Êý¶þ 323 Çóµ÷¼Á +10 Ô¬sy 2026-04-01 10/500 2026-04-02 19:52 by xingsh
[¿¼ÑÐ] 282Çóµ÷¼Á +13 ºôÎü¶¼ÊǼõ·Ê 2026-04-01 13/650 2026-04-02 14:10 by baoball
[¿¼ÑÐ] 08¿ªÍ·¿´¹ýÀ´£¡£¡£¡ +4 wwwwffffff 2026-03-31 6/300 2026-04-02 11:42 by ¾ùÖµ»Ø¹é
[¿¼ÑÐ] Ò»Ö¾Ô¸9³õÊÔ366 ±¾Ë«·ÇÇóµ÷¼Á +4 ÔËÆøÀ´µÃÈôÓÐËÆÎ 2026-04-02 4/200 2026-04-02 09:56 by guanxin1001
[¿¼ÑÐ] ʡ˫һÁ÷ÖØµãÒ»±¾´óѧÕÐÊÕµ÷¼Á +4 wwwwffffff 2026-03-31 7/350 2026-04-01 15:23 by wwwwffffff
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û