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nx8011

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[交流] 大家帮看一下这个审稿意见棘手不，谢谢了。

主编给的大修，一审只用了20天。
Dear Mr. --,

We have received the reports from our advisors on your manuscript, "--", which you submitted to ---.

Based on the advice received, I have decided that your manuscript could be reconsidered for publication should you be prepared to incorporate major revisions. When preparing your revised manuscript, you are asked to carefully consider the reviewer comments which can be found below, and submit a list of responses to the comments. You are kindly requested to also check the website for possible reviewer attachment(s).

In order to submit your revised manuscript, please access the following web site:

-----

We look forward to receiving your revised manuscript before 05 Oct 2013.

With kind regards,
-----
Editor in Chief

COMMENTS FOR THE AUTHOR:

Reviewer #1: General comment: This is an interesting study on the acaricidal effects -----. However, all sections of the manuscript need to be revised. The English should be completely revised. More detailed comments are reported below.
Abstract:
The Abstract is too long and should be considerably reduced.
Introduction:
Line 39 page 3: Chorioptes species can infest also outer ear canals and the face of ungulates (see Gete Hestvik et al. Acta Veterinaria Scandinavica 2007, 49:21; http://entomology.cornell.edu/extension/vet/aid/cow/mites.cfm);
Lines 56-59 page 3: the name of these acaricidal compounds should be written in lowercase;
Lines 20-37 page 4: this part should be shortened by including only the biological activities of --- and the related references;
Line 42 page 4: Replace -- with --;
Materials and methods:
Lines 28-45 page 5: Since petroleum has a strong acaricidal activity, are the authors sure that all petroleum ether was evaporated from the extract?
Lines 9-17 page 6: the number and the date of the experimental protocol approved by an animal welfare committee is lacking;
Lines 29-59 page 6: in many cases the same methods were used in the different studies reported in the references of this section;
Lines 20-56 page 7: the method used to evaluate the number of mites/animal is incorrect, in fact the number of mites/cm2 of a same infected area/animal should be calculated. In addition, differently by what stated by the authors, parameters used for the evaluation of the reduction of mite number are not reported in Table 1.
Line 1 page 8: replace "preliminary analyze the principal active compounds in the petroleum-ether E. adenophorum extract" with "preliminary evaluation of the principal components of E. adenophorum petroleum-ether extract".
Results:
Lines 45-59 page 8: since from results obtained in this study the in vitro acaricidal activity of -- ethanol thermal circumfluence extract appears higher than that of the -- petroleum-ether extract (see also Lines 9-26 page 9), why the latter and not the former was chosen to evaluate the in vivo acaricidal activity of ---?

Lines 12-28 page 10: the study would have been much more interesting and scientifically correct if the authors had identified these main constituents.
Discussion
Lines 47-53 page 10: the authors are really sure that the antibiotics are effective for the treatment of chorioptic mange?
Line 59 page 10: the authors are really sure that this extract is environmentally-friendly? For example, natural pyrethrum-based acaricides are not so environmentally-friendly! In any case, a reference is needed for this statement.
References:
References should be completely revised both in the text and in the Reference list. In general, an excessive number of references have been reported and should be reduced, limiting to one or two more significant and recent references per point. In addition, in many cases references reported in the text are lacking in the reference list (see Brien, 1999 and Wang et al., 2012) or they are wrongly reported (see Silvia et al., 2010). Moreover, the references with a same first author in the same year have not been distinguished by using the letters of the alphabet (both in the text and in the reference list, see Rehbein et al., 2003). Furthermore, in the Reference list the name of the first authors are not reported in alphabetic order, nor the references with the same first author are in chronological order. Finally, the names of genus and species are not in italics.
Tables:
Table 1 and Table 5 might be merged in a single Table.
Figures:
Figure 1 is not necessary.
The legend of the Figure 2 is not self-explanatory.

COMMENT FROM THE EDITOR: NORMALLY A MANUSCRIPT WITH THIS MANY CONCERNS IS REJECTED, BUT THERE ARE SOME POSITIVE ASPECTS, AND IF THESE CONCERNS ARE PROPERLY WE WOULD CONSIDER PUBLICATION

1.    AS NOTED BY THE REFEREE, AT THE TOP OF THE LIST IS A COMPLETE RE-WRITE OF THE MANUSCRIPT BY AN EXPERT IN ENGLISH, PRFERRABLY WITH A SCIENCE BACKGROUND. IF THIS IS NOT DONE WE WILL CEASE PROCESSING THE MANUSCRIPT FURTHER. THUS, PLEASE DO NOT RETURN THE MANUSCRIPT UNLESS THE ENGLISH IS FIXED.

2.    PLEASE RESPOND TO THE REFEREE’S COMMENTS IN A POINT-BY-POINT MANNER. IT HELPS IF YOU WRITE THE WORD "RESPONSE" (IN CAPITAL LETTERS) AFTER EACH COMMENT BY THE REFEREE, AND THEN ADD YOUR RESPONSE.

3.    SINCE ANIMALS WERE USED IN THIS WORK, IT IS NECESSARY TO PROVIDE A  STATEMENT FROM THE BODY/COMMITTEE THAT OVERSEES AND GIVES APPROVAL FOR USE OF ANIMALS IN RESEARCH AT YOUR INSTITUTION . WITHOUT SUCH A STATEMENT WE CANNOT CONSIDER PUBLICATION. THIS CAN BE PLACED IN THE "MATERIALS AND METHODS" SECTION

4.    THE PUNCTUATION ASSOCIATED WITH THE AUTHOR CITATIONS IN THE BODY OF THE MANUSCRIPT AND IN THE REFERENCE SECTION DOES NOT CONFORM WITH THE PARASITOLOGY RESEARCH FORMAT. FOR THIS I WILL SEND A SEPARATE EMAIL WITH AN ATTACHED PAGE FROM THE JOURNAL FOR AN EXAMPLE OF THE STYLE TO BE USED.

5.    SOME ENTRIES IN THE REFERENCE SECTION HAVE THE et al. DESIGNATION. ALL AUTHORS MUST BE INCLUDED

6.    AS POINTED OUT BY THE REVIEWER, THERE ARE TOO MANY REFERENCES.THESE SHOULD BE REDUCED TO INCLUDE THOSE THAT ARE DIRECTLY ASSOCIATED WITH THIS WORK

7.    ALL SCIENTIFIC NAMES MUST BE IN ITALICS

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