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杜小丫

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[交流] 每周一听——那些年我们一起练过的听力(第122期) 已有24人参与

每周一听——那些年我们一起练过的听力(第122期)


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          Successful gene therapy to correct a host of devastating diseases has been elusive. But researchers may have gotten a step closer with a treatment for Parkinson's disease, the second most common neuro-degenerative condition after Alzheimer's disease.
Neurologist Michael Kaplitt at the Weill College Medicine at Cornell University in New York says Parkinson's    (1)    the ability of patients to move, and the gene therapy helped them to move.
"The symptoms are tremors and stiffness, freezing, you know, muscle stiffness," he said. "So,when you put that all together as sort of a composite, we saw there was a significant improvement in these patients over time that lasted for the full one year of the study."
Kaplitt says there is a group of cells in the    (2)    of the brain that controls movement through production of a chemical called dopamine. In Parkinson's disease, Kaplitt says, the cells stop producing dopamine and the movement control center becomes    (3)    .
In the    (4)    of the disease, Parkinson's symptoms can be quieted with drugs that replace dopamine. But as the disease progresses, the drugs make the symptoms worse. So, Kaplitt and colleagues decided to try to    (5)    the dopamine-producing cells to see if they could alter regulation of movement at a higher brain level.
Researchers developed a therapy in which they    (6)    a modified gene to viral  particles and infused the treatment into one side of the brain of 12 participants with varying degrees of Parkinson's symptoms.
The gene, called GABA, helps in the production of a chemical that has a    (7)    effect over a wider area of the brain.
Kaplitt says investigators were hoping for lasting results.
"The idea was, with a single    (8)    at a single site, putting in this one gene there, that you would create a little factory that would essentially reestablish the normal neuro-chemical balance of a large part of this circuit to normalize the flow of information to the rest of the brain and thereby hopefully improve symptoms," he explained.
Kaplitt says it took three months for the therapy to    (9)    in, but once it did, most   patients showed significant improvement of their symptoms up to one year after the therapy.  He says for some patients, the improvements were not as    (10)    or did not last as long.
The study was completed in May 2006 and its results were published in the latest issue of The Lancet.






         
上期活动答案:
1.areas
2. distracts
3. construction
4. spatial
5.dimensions
6.observations
7. blocks
8.participate
9. encourage
10.applications


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wwfiresure

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杜小丫: 金币+15 2015-02-01 17:56:16
Go away, Parkinson
7楼2015-01-31 23:48:33
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杜小丫

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杜小丫: 回帖置顶 2015-01-31 17:54:09
1.        areas
n. 区域,领域;面积
例:
Local authorities have been responsible for the running of schools in their areas.
地方政府一直负责其辖区内各校的运作

2. distracts
vt. 转移;分心
例:
Tom admits that playing video games sometimes distracts him from his homework.
汤姆承认玩电子游戏有时让他做家庭作业时分心。

3. construction
•        n. 建设;建筑物;解释;造句
例:
He'd already started construction on a hunting lodge.
他已经开始建造一个狩猎用的小屋。

4. spatial
•        adj. 空间的;存在于空间的;受空间条件限制的
例:
His manual dexterity and fine spatial skills were wasted on routine tasks.
他的手巧和很好的感悟空间的技能被浪费在日常事务中了。

5.dimensions
•        n. 规模,大小
例:
There is a political dimension to the accusations.
这些指控含有政治因素。

6.observations
n. 观察,观察值;观察结果;
例:
This book contains observations about the causes of addictions.
这本书包含关于上瘾原因的观察结果。

7. blocks
•        n. [建] 街区;积木;楼群
•        v. 阻碍;封锁;使成块
例:
He walked around the block three times.
他绕着这个街区走了3圈。
•       

8.participate
•        vi. 参与,参加;分享
•        vt. 分享;分担
例:
They expected him to participate in the ceremony.
他们希望他参加这个典礼

9. encourage
•        vt. 鼓励,怂恿;激励;支持
例:
When things aren't going well, he encourages me, telling me not to give up.
当事情不顺利的时候,他鼓励我,告诉我不要放弃。

10.applications
n. 应用;应用程序;应用软件
例:
His application for membership of the organization was rejected.
他对该组织会员资格的申请被拒绝了。
2楼2015-01-31 17:53:45
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玲V平常心

新虫 (正式写手)

好的,嗯嗯,试试

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4楼2015-01-31 19:45:04
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yujwly

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杜小丫: 金币+5, 嘿嘿,肯定会休息的,谢谢关心 2015-02-06 23:05:29
杜小丫: 金币+5, 嘿嘿,肯定会休息的,谢谢关心 2015-02-06 23:10:45
版主辛苦了!寒假开始了!轻松一下!
Lifeistough!
5楼2015-01-31 22:25:52
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