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北京石油化工学院2026年研究生招生接收调剂公告
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icebergwu

木虫之王 (文学泰斗)

[求助] 麻烦虫友帮我润色一下这段话

中文:普拉特霉素是一种大环内酯类抗生素。本文建立了一种利用A将麦迪霉素转化为普拉特霉素的方法,发酵产量达到5.528g/L。通过调节pH进行反复沉淀溶解粗提取与ODS反相层析分离精提取相结合的方法对发酵液中的普拉特霉素A1进行分离纯化,得到纯度为97.74%的纯品,对所得纯品进行了MALDI-TOF-MS和NMR检测,确定了所得物质为普拉特霉素。对提纯后的普拉特霉素A1进行了体外药效试验,验证了普拉特霉素对Staphyloccocus aureu、Streptococcus pneumoniae和Septic Streptococcus和Porcine Actinobacillus pleuropneumoniae都具有较好的药物敏感性。
英文:Platenomycin is a macrolide antibiotic. The process for producing antibiotic composition Platenomycin by bioconversion of Midecamycin by A was investigated. The highest yield of Platenomycin was 5.654g/L. Recovering the antibiotic from the fermentation broth by adjusting the pH, and purifying the crude residue to 97.74%. The purified compound was identified as Platenomycin by MALDI-TOF-MS and NMR. Results demonstrated that this macrolide is active against Staphyloccocus aureu、Streptococcus pneumoniae、Septic Streptococcus and Porcine Actinobacillus pleuropneumoniae.
我翻译了一下,但是觉得不太正宗,麻烦英语好的虫友帮我润色一下!谢谢!

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xianghuayu

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RXMCDM: 金币+1, 多谢应助! 2014-02-28 22:48:32
icebergwu: 金币+8, 翻译EPI+1 2014-03-01 11:19:18
The preparation of Platenomycin,  a macrolide antibiotic, through bioconversion of Midecamycin using A was investigated, giving the highest yield of Platenomycin at 5.654g/L. A purity of 97.74% was achieved after recovering the antibiotic from the fermentation broth through adjusting pH, and multiple purification of the crude residue. The final compound was verified as Platenomycin by MALDI-TOF-MS and NMR. Clinical results demonstrate that the macrolide is active against Staphyloccocus aureu, Streptococcus pneumoniae, Septic Streptococcus, and Porcine Actinobacillus pleuropneumoniae.
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2楼2014-02-28 22:10:20
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RXMCDM

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icebergwu: 金币+12, ★★★★★最佳答案 2014-03-01 11:19:27
Platenomycin is a kind of macrolide antibiotic. By using A,we established a method to turn  Midecamycin  into  Pratt neomycin ,with which fermentation production    come to  5.528g / L.  Through adjusting the PH  to repeatedly precipitation and dissolve the crude extract  combined  with  ODS reversed phase chromatography method ,the Pratt ADM A1 in the fermentation broth were isolated and purified.The product is of  97.74%  purity   and identified of Pratt neomycin by MALDI-TOF-MS and NMR detection. In vitro efficacy trials conducted   of  the purified Pratt ADM  A1  verified  that Pratt ADM  has  better drug sensitivity on Staphyloccocus aureu,Streptococcus pneumoniae,Septic Streptococcus and Porcine Actinobacillus pleuropneumoniae.
3楼2014-02-28 22:47:06
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icebergwu

木虫之王 (文学泰斗)

引用回帖:
2楼: Originally posted by xianghuayu at 2014-02-28 22:10:20
The preparation of Platenomycin,  a macrolide antibiotic, through bioconversion of Midecamycin using A was investigated, giving the highest yield of Platenomycin at 5.654g/L. A purity of 97.74% was a ...

谢谢!
4楼2014-03-01 11:19:48
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icebergwu

木虫之王 (文学泰斗)

引用回帖:
3楼: Originally posted by RXMCDM at 2014-02-28 22:47:06
Platenomycin is a kind of macrolide antibiotic. By using A,we established a method to turn  Midecamycin  into  Pratt neomycin ,with which fermentation production    come to  5.528g / L.  Through adju ...

谢谢!
5楼2014-03-01 11:19:56
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