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【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ RXMCDM: 金币+1, 多谢应助! 2014-02-28 22:48:32 icebergwu: 金币+8, 翻译EPI+1 2014-03-01 11:19:18
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The preparation of Platenomycin, a macrolide antibiotic, through bioconversion of Midecamycin using A was investigated, giving the highest yield of Platenomycin at 5.654g/L. A purity of 97.74% was achieved after recovering the antibiotic from the fermentation broth through adjusting pH, and multiple purification of the crude residue. The final compound was verified as Platenomycin by MALDI-TOF-MS and NMR. Clinical results demonstrate that the macrolide is active against Staphyloccocus aureu, Streptococcus pneumoniae, Septic Streptococcus, and Porcine Actinobacillus pleuropneumoniae. |
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