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Reviewer #1: The manuscript was written in a good manner for scientific publication, however the aim and described study are still weak and lacking. Considering to the benefit of ... , the author encourage to include economical point of view of the study since indeed this is the native aim and interesting part of the study. The study should construct a preliminary red line connection to the industrial scale. Otherwise, if the authors prefer to focus deeper into enzyme production technology, they should add analysis of bioprocess engineering for being sufficient in international publication. Therefore it's very important to do major revision for the manuscript.

[ Last edited by seapass on 2013-6-7 at 12:25 ]
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