The drug is the weak acid and has a molecular weight of 356 and a pKa of 2.76. The drug is dissolved in isotonic NaC1 solution (0.9 g NaC1 per 100 mL) to make a 3% w/v solution. What is the pH of this solution (disregarding activity)? What the pH of this solution using ionic activity coefficients? (remember the Debye-Huckel equation).
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