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smilesir

银虫 (小有名气)

[求助] 编辑发回让小修(动物分子育种类的文章),一个问题想请教一下如何回答,谢谢!

审稿人意见如下:The description of statistical analyses is unclear. It needs to be thoroughly rephrased. What is the reason of using both SPSS and SAS programs? Animal model is not implemented in SPSS or SAS programs unless not mentioned author libraries or functions have been used.
Have association analyses been carried out on direct additive breeding values?

我的论文内容如下:
Statistical analysis
Statistical analysis of associations between genotypes and the selected traits of F2 chickens were carried out using SPSS 19.0 according to the following linear mixed model:
Yijklm=μ+Gi+Sj+Hk+fl +eijklm
Where, Yijklm is the dependent variable (analyzed traits); μ is the overall mean; Gi is the fixed effect of genotype or haplotype; Sj is the fixed effect of sex; Hk is the fixed effect of hatch, fl is the random effect of family, eijklm is the random error.
The SNP-traits association analysis was done in two steps. First, we used the full animal model which included fixed effects of marker genotype, sex, hatch and a random effect of family. Second, on the basis of the first step, we used the reduced animal model in order to exclude the effects that did not have a significant influence (p>0.05) on the variability of traits.
SAS 8.0 program was used to analyze the additive and dominance effects of the SNP which has significant associations with the selected traits by REG procedure (additive effect with -1, 0 and 1 representing GG (TT), GA (TG) and AA (GG) genotypes, respectively; dominant effect with 1, -1 and 1 representing GG (TT), GA (TG) and AA (GG) genotypes, respectively.

用SAS是因为当时用SAS验证一下发现结果一致,就手贱的多写了个SAS,晕。。。
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smilesir

银虫 (小有名气)

原来是这个意思Presented linear mixed model is a family (sire-dam) model and not an animal one which is related to A (the numerator relationship matrix - Henderson, 1973). As far as I know, neither SAS nor SPSS build A matrix directly, so they do not use the animal model. Moreover, SAS and SPSS are operationally similar statistical packages.
9楼2012-08-02 17:09:08
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sesame_oil

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【答案】应助回帖

感谢参与,应助指数 +1
实话实说吧,审稿人一般都很开明
不是哥不笑,一笑粉就掉
2楼2012-06-08 22:49:06
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smilesir

银虫 (小有名气)

引用回帖:
2楼: Originally posted by sesame_oil at 2012-06-08 22:49:06
实话实说吧,审稿人一般都很开明

那这个问题Animal model is not implemented in SPSS or SAS programs unless not mentioned author libraries or functions have been used.
Have association analyses been carried out on direct additive breeding values? 是想说些什么呢?
3楼2012-06-09 11:29:09
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啸天犬

至尊木虫 (职业作家)

【答案】应助回帖

感谢参与,应助指数 +1
What is the reason of using both SPSS and SAS programs? Animal model is not implemented in SPSS or SAS programs unless not mentioned author libraries or functions have been used.
Have association analyses been carried out on direct additive breeding values?
为什么用了SPSS和SAS两个软件?SPSS和SAS软件中并没有执行Animal model (这块不是很明白)。对direct additive breeding values做没做其它的相关的分析?
天下兴亡,我的责任!
4楼2012-06-09 11:52:00
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