在投文章时,审稿人给了这样的评语:The main problem is the incorrect assignment of H atoms on the terminal N of the hydrazide. This N atom takes a pyramidal rather than planar geometry. The incorrect structure shows very short H...H contacts, which are clearly impossible. The authors should use difference Fourier maps to determine the correct orientation of the H(-N) atoms, then refine them in riding mode with the appropriate N-H distance constraint.