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112976553

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½á¹û  ·úµ¥¶ÀȾ¶¾×é´óÊó·ú°ßÑÀÖ¢×´Ã÷ÏÔ¡£ÓëÈܼÁ¶ÔÕÕ×éÏà±È£¬·úµ¥¶ÀȾ¶¾×é´óÊó¸ÎÔàÖÐGSH-Px¡¢SOD»îÁ¦½µµÍ£¬MDAº¬Á¿Éý¸ß£¬²îÒì¾ùÓÐͳ¼ÆÑ§ÒâÒå(P<0.05)£»¸ßŨ¶ÈÎøµ¥¶ÀȾ¶¾×éSOD»îÁ¦½µµÍ£¬²îÒì¾ùÓÐͳ¼ÆÑ§ÒâÒå(P<0.05)¡£Óë·úµ¥¶ÀȾ¶¾×éÏà±È£¬ÖС¢¸ßŨ¶ÈÎøµ¥¶ÀȾ¶¾×éºÍ¸ßŨ¶ÈÎø+·úÁªºÏȾ¶¾×é´óÊó¸ÎÔàÖÐGSH-Px»îÁ¦ÉÏÉý£¬²îÒì¾ùÓÐͳ¼ÆÑ§ÒâÒå(P<0.05»òP<0.01)£»µÍ¡¢ÖÐŨ¶ÈÎøµ¥¶ÀȾ¶¾×éSOD»îÁ¦ÉÏÉý£¬²îÒì¾ùÓÐͳ¼ÆÑ§ÒâÒå(P<0.05)£»ÖÐŨ¶ÈÎøµ¥¶ÀȾ¶¾×éºÍ¸ßŨ¶ÈÎø+·úÁªºÏȾ¶¾×éMDAº¬Á¿Ï½µ£¬²îÒì¾ùÓÐͳ¼ÆÑ§ÒâÒå(P<0.05)¡£¸÷Ⱦ¶¾×é´óÊó¸ÎÔàÖÐT-AOC»îÁ¦¼ä±È½Ï£¬²îÒìÎÞͳ¼ÆÑ§ÒâÒå¡£ÓëÈܼÁ¶ÔÕÕ×éÏà±È£¬·úµ¥¶ÀȾ¶¾×éºÍµÍŨ¶ÈÎø+·úÁªºÏȾ¶¾×é´óÊó¸Î×éÖ¯ÖÐNF-¦ÊB±í´ïˮƽÉý¸ß£¬²îÒì¾ùÓÐͳ¼ÆÑ§ÒâÒå(P<0.05)¡£Óë·úµ¥¶ÀȾ¶¾×éÏà±È£¬µÍŨ¶ÈÎøµ¥¶ÀȾ¶¾×é´óÊó¸Î×éÖ¯ÖÐNF-¦ÊB±í´ïˮƽ½µµÍ£¬²îÒìÓÐͳ¼ÆÑ§ÒâÒå(P<0.05)¡£²¡Àíѧ½á¹ûÏÔʾ£¬·ú+ÎøÁªºÏȾ¶¾×é´óÊó¸Îϸ°û±äÐÔ»µËÀ³Ì¶ÈÃ÷ÏÔ¼õÇᣬÇÒ¸Îϸ°û±äÐÔ»µËÀ³Ì¶ÈËæ×ÅÎøÈ¾¶¾Å¨¶ÈµÄÉý¸ß¶ø³ÊϽµÇ÷ÊÆ¡£

Results  Fluoride single exposure group showed obvious symptoms of dental fluorosis. Compared with the control, the GSH-Px, SOD activity in rat liver from fluoride single exposure group decreased, and MDA content increased, the differences were statistically significant (P <0.05); the SOD activity of high concentrations of selenium single exposure group reduced, the differences were statistically significant (P <0.05). Compared with single exposure group, the GSH-Px activity of high concentrations of selenium single exposure group and the high concentration of selenium-fluoride combined exposure group in rat liver increased, the differences were statistically significant (P <0.05 or P <0.01); the SOD activity of low concentrations and middle concentrations of selenium in the single exposure group increased, the differences were statistically significant (P <0.05); the MDA content of middle concentration of selenium single exposure group and the high concentration of fluoride- selenium combined exposure group was decreased, the differences were statistically significant (P <0.05). The differences of T-AOC activity in Liver of rats among all exposure groups difference were not statistically significant. Compared with the control group, NF-¦ÊB expression level in rat liver from fluoride single exposure group and the low fluoride concentration combined with selenium exposure group, the differences were statistically significant (P <0.05). compared with Fluoride single exposure group, the NF-¦ÊB expression level in rat liver from low concentration of selenium single exposure group decreased significantly (P <0.05). Pathology results showed the rats from fluoride-selenium combined exposure ameliorate significantly the degeneration and necrosis of liver cells, and the extent of degeneration and necrosis of liver cells decreased with the rise of the concentration of selenium.

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zerohead

½û³æ (Ö°Òµ×÷¼Ò)

112976553(½ð±Ò+8, ·­ÒëEPI+1):ÂÔ×öÐ޸ģ¬ÐÁ¿àÁË£¬½±ÀøÎå¸ö½ð±Ò£¬Ï£ÍûÄܶà¸Ä³öÀ´µã£¬ÎÒÒ²¿É¶àËͽð±Ò 2010-08-13 21:36:51
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Most of the rats which received fluoride single exposure (Group x) showed obvious symptoms of dental fluorosis. Compared with the control group, the activities of GSH-Px, SOD in livers of the rats from the single exposure group decreased, while the MDA content increased. For the high concentration selenium single exposure group, the SOD activity is reduced. All of the measurements in the current study have a statistically significant value of less than 0.05 (or better).
2Â¥2010-08-13 20:15:28
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zerohead

½û³æ (Ö°Òµ×÷¼Ò)

112976553(½ð±Ò+1):лл°ï棬Óе㳤ÁË 2010-08-14 09:04:39
Quantity and quality is sometimes hard to be distinguished, but the difference between them is such huge that no any statistically significant value can be estimated.
3Â¥2010-08-13 22:13:56
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rbhuang

ľ³æ (ÕýʽдÊÖ)

112976553(½ð±Ò+20):¸ÄµÃºÜºÃ£¬ÒѾ­²Î¿¼Ñ¡Óã¬Ð»Ð»£¡ 2010-08-15 12:47:36
Results  The group with fluoride single exposure showed obvious symptoms of dental fluorosis. Compared with the control, the GSH-Px, SOD activity in rat livers from the group with fluoride single exposure decreased, and MDA content increased (P <0.05).  The SOD activity from the group with high concentration selenium single exposure reduced, with statistical significance (P <0.05). Compared with single exposure group, the GSH-Px activity in rat livers from the group with high concentration selenium single exposure and those with high concentration of combined selenium-fluoride exposure increased, the differences were also statistically significant (P <0.05 or P <0.01); the SOD activities from the groups with low and middle concentrations of selenium single exposure increased (P <0.05); the MDA contents from the group with middle concentration selenium single exposure and the group with high concentration of combined fluoride- selenium exposure were decreased (P <0.05). The differences of T-AOC activity in the livers of rats among all exposure groups were not statistically significant. Compared with the control group, the differences of NF-¦ÊB expression level in rat livers from the group with fluoride single exposure and those combined with low fluoride concentration selenium exposure were statistically significant (P <0.05). Compared with fluoride single exposure group, the NF-¦ÊB expression level in rat livers from the group with low concentration of selenium single exposure decreased significantly (P <0.05). Pathological results showed that the rats from combined fluoride-selenium exposure significantly ameliorated the degeneration and necrosis of liver cells, and the extent of these decreased with the rise of selenium concentration.

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361468801

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112976553(½ð±Ò+30):ÒѲÉÓã¬Ð»Ð»~ 2010-08-15 19:44:58
·¢Ñ¿ÍÁ¶¹:This is a suspicious IP! 2010-08-17 10:27:07
The group with fluoride single exposure showed obvious symptoms of dental fluorosis. Compared with the control, the activity of GSH-Px, SOD in rat liver from the group with fluoride single exposure decreased, and the MDA content increased (P <0.05); the SOD activity from the group with high concentration selenium single exposure reduced, with statistical significance(P <0.05). Compared with fluoride single exposure group, the GSH-Px activity in rat livers from the groups with middle, high concentration selenium single exposure and those with high concentration of combined selenium-fluoride exposure increased, the differences were also statistically significant (P <0.05 or P <0.01); the SOD activity from the groups with low and middle concentrations of selenium single exposure increased (P <0.05); the MDA contents from the group with middle concentration selenium single exposure and the group with high concentration of combined fluoride-selenium exposure were decreased (P <0.05). The differences of T-AOC activity in the Livers of rats among all exposure groups were not statistically significant. Compared with the control, the difference of NF-¦ÊB expression level in rat livers from the group with fluoride single exposure and those with low selenium-fluoride exposure increased, the differences were statistically significant (P <0.05).Compared with fluoride single exposure group, the NF-¦ÊB expression level in rat livers from the group with low concentration of selenium single exposure decreased (P <0.05). Pathology results showed that the rats from combined fluoride-selenium exposure significantly ameliorate the degeneration and necrosis of liver cells, and the extent of these decreased with the rise of selenium concentration.
5Â¥2010-08-15 19:37:57
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rbhuang

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·¢Ñ¿ÍÁ¶¹(½ð±Ò+3):Thank you for reporting the information! 2010-08-17 10:47:22
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