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汕头大学海洋科学接受调剂
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eveb

木虫 (正式写手)

[交流] 大家帮忙看一下二审意见.几个疑问请高手指点,谢谢

文章经过初审让大修.大修后经二审,意见如下
Reviewer #1: The paper has been clearly improved. However, the effects of bFGF gene silencing on glioma cell proliferation remain rather low.
Minor point: the authors should label the x-axis of the diagram in Fig. 4.

Reviewer #2: The authors have responded to most of the reviewers comments, but serious reservations remain.
The biggest issue is that the effects observed are fairly modest, and do not provide convincing evidence that this approach will lead anywhere in glioma therapy.
This could potentially be rescued by survival studies, or combinations with chemotherapeutics as suggested in the previous round of comments. The use of glioma stem-like cells may also help, as these may be more responsive to this approach.

MINOR POINTS
1. the cell line should be referred to as LN229 rather than L229.
2. Exposure for the scratch assay shown in figure 2 is very uneven.

现有个疑问.请高指点一下评阅人的这几句话用回答吗

Reviewer #1: The paper has been clearly improved. However, the effects of bFGF gene silencing on glioma cell proliferation remain rather low.

Reviewer #2: The authors have responded to most of the reviewers comments, but serious reservations remain.
The biggest issue is that the effects observed are fairly modest, and do not provide convincing evidence that this approach will lead anywhere in glioma therapy.

This could potentially be rescued by survival studies, or combinations with chemotherapeutics as suggested in the previous round of comments. The use of glioma stem-like cells may also help, as these may be more responsive to this approach.

还是只回答下面的几点就可以
Minor point: the authors should label the x-axis of the diagram in Fig. 4.
MINOR POINTS
1. the cell line should be referred to as LN229 rather than L229.
2. Exposure for the scratch assay shown in figure 2 is very uneven.

高手指点.谢谢
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ljl8209

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eveb(金币+1,VIP+0): 10-27 21:21
都要认真回答的  前面的更重要一些, 后面的应该容易搞定
7楼2009-10-27 17:09:27
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今天来灌水

铁杆木虫 (职业作家)


eveb(金币+1,VIP+0):2 10-27 15:20
前面两点也要做出说明或解释!
2楼2009-10-27 12:07:45
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weiswallow

铁杆木虫 (职业作家)


eveb(金币+1,VIP+0): 10-27 15:20
不管是什么,只要是审稿意见,都必须要认真回答与解释
学无止境
3楼2009-10-27 13:54:30
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liwenbin0929

新虫 (正式写手)


eveb(金币+1,VIP+0): 10-27 15:21
楼上两位说的很对,对审稿人提出的异议必须做回复,要修改的地方也肯定是要改的。态度决定一切
4楼2009-10-27 13:59:05
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