Znn3bq.jpeg
ÉÇÍ·´óѧº£Ñó¿ÆÑ§½ÓÊܵ÷¼Á
²é¿´: 554  |  »Ø¸´: 6
µ±Ç°Ö÷ÌâÒѾ­´æµµ¡£
µ±Ç°Ö»ÏÔʾÂú×ãÖ¸¶¨Ìõ¼þµÄ»ØÌû£¬µã»÷ÕâÀï²é¿´±¾»°ÌâµÄËùÓлØÌû

eveb

ľ³æ (ÕýʽдÊÖ)

[½»Á÷] ´ó¼Ò°ï濴һ϶þÉóÒâ¼û.¼¸¸öÒÉÎÊÇë¸ßÊÖÖ¸µã,лл

ÎÄÕ¾­¹ý³õÉóÈôóÐÞ.´óÐÞºó¾­¶þÉó,Òâ¼ûÈçÏÂ
Reviewer #1: The paper has been clearly improved. However, the effects of bFGF gene silencing on glioma cell proliferation remain rather low.
Minor point: the authors should label the x-axis of the diagram in Fig. 4.

Reviewer #2: The authors have responded to most of the reviewers comments, but serious reservations remain.
The biggest issue is that the effects observed are fairly modest, and do not provide convincing evidence that this approach will lead anywhere in glioma therapy.
This could potentially be rescued by survival studies, or combinations with chemotherapeutics as suggested in the previous round of comments. The use of glioma stem-like cells may also help, as these may be more responsive to this approach.

MINOR POINTS
1. the cell line should be referred to as LN229 rather than L229.
2. Exposure for the scratch assay shown in figure 2 is very uneven.

ÏÖÓиöÒÉÎÊ.Çë¸ßÖ¸µãÒ»ÏÂÆÀÔÄÈ˵ÄÕ⼸¾ä»°ÓûشðÂð

Reviewer #1: The paper has been clearly improved. However, the effects of bFGF gene silencing on glioma cell proliferation remain rather low.

Reviewer #2: The authors have responded to most of the reviewers comments, but serious reservations remain.
The biggest issue is that the effects observed are fairly modest, and do not provide convincing evidence that this approach will lead anywhere in glioma therapy.

This could potentially be rescued by survival studies, or combinations with chemotherapeutics as suggested in the previous round of comments. The use of glioma stem-like cells may also help, as these may be more responsive to this approach.

»¹ÊÇÖ»»Ø´ðÏÂÃæµÄ¼¸µã¾Í¿ÉÒÔ
Minor point: the authors should label the x-axis of the diagram in Fig. 4.
MINOR POINTS
1. the cell line should be referred to as LN229 rather than L229.
2. Exposure for the scratch assay shown in figure 2 is very uneven.

¸ßÊÖÖ¸µã.лл
»Ø¸´´ËÂ¥

» ²ÂÄãϲ»¶

ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

weiswallow

Ìú¸Ëľ³æ (Ö°Òµ×÷¼Ò)

¡ï
eveb(½ð±Ò+1,VIP+0): 10-27 15:20
²»¹ÜÊÇʲô£¬Ö»ÒªÊÇÉó¸åÒâ¼û£¬¶¼±ØÐëÒªÈÏÕæ»Ø´ðÓë½âÊÍ
ѧÎÞÖ¹¾³
3Â¥2009-10-27 13:54:30
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
²é¿´È«²¿ 7 ¸ö»Ø´ð

½ñÌìÀ´¹àË®

Ìú¸Ëľ³æ (Ö°Òµ×÷¼Ò)

¡ï
eveb(½ð±Ò+1,VIP+0):2 10-27 15:20
Ç°ÃæÁ½µãÒ²Òª×ö³ö˵Ã÷»ò½âÊÍ!
2Â¥2009-10-27 12:07:45
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

liwenbin0929

гæ (ÕýʽдÊÖ)

¡ï
eveb(½ð±Ò+1,VIP+0): 10-27 15:21
Â¥ÉÏÁ½Î»ËµµÄºÜ¶Ô£¬¶ÔÉó¸åÈËÌá³öµÄÒìÒ鱨Ðë×ö»Ø¸´£¬ÒªÐ޸ĵĵط½Ò²¿Ï¶¨ÊÇÒª¸ÄµÄ¡£Ì¬¶È¾ö¶¨Ò»ÇÐ
4Â¥2009-10-27 13:59:05
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

realmadrider

Ìú¸Ëľ³æ (ÖøÃûдÊÖ)

¡ï
eveb(½ð±Ò+1,VIP+0): 10-27 15:21
ÒýÓûØÌû:
»¹ÊÇÖ»»Ø´ðÏÂÃæµÄ¼¸µã¾Í¿ÉÒÔ
Minor point: the authors should label the x-axis of the diagram in Fig. 4.
MINOR POINTS
1. the cell line should be referred to as LN229 rather than L229.
2. Exposure for the scratch assay shown in figure 2 is very uneven.

ÕâЩ¶¼ÊÇMINORµÄÎÊÌâ£¬Ç°ÃæµÄ²ÅÊÇMAJORµÄÎÊÌ⣬ºÃºÃ»Ø´ðÉó¸åÈ˵ÄÎÊÌâ
5Â¥2009-10-27 14:22:44
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] һ־Ը³¶«´óѧ071000ÉúÎïѧѧ˶³õÊÔ·ÖÊý276Çóµ÷¼Á +22 Ľ¾øcc 2026-04-09 26/1300 2026-04-14 13:14 by wanganpin
[¿¼ÑÐ] Çóµ÷¼Á +19 MAXâê㯠2026-04-09 21/1050 2026-04-14 11:11 by ²»ÎÒÀ­ÂÌ¿¨
[¿¼ÑÐ] 279ѧ˶ʳƷרҵÇóµ÷¼ÁԺУ 20+6 ¹Â¶ÀµÄÀǰ®³ÔÑò 2026-04-12 26/1300 2026-04-14 09:04 by zs92450
[¿¼ÑÐ] µ÷¼ÁÇóÊÕÁô +32 ¹ûÈ»ÓÐÎÒ 2026-04-10 33/1650 2026-04-14 08:49 by ľľmumu¡«
[¿¼ÑÐ] Çóµ÷¼Á +12 Á§ÜÔÒ»¶¨Éϰ¶ 2026-04-10 13/650 2026-04-14 00:08 by Equinoxhua
[¿¼ÑÐ] ±¾¿ÆÎ÷¹¤´ó 324Çóµ÷¼Á +5 wysyjs25 2026-04-10 5/250 2026-04-13 23:08 by pies112
[¿¼ÑÐ] µ÷¼Á +27 ²»·ê´º 2026-04-07 28/1400 2026-04-13 20:19 by xxy88888
[¿¼ÑÐ] 335Çóµ÷¼Á +18 ÏëÉϰ¶Ñ½£¡£¡ 2026-04-12 19/950 2026-04-13 14:15 by ÕÅzhihao
[¿¼ÑÐ] 266µ÷¼Á +10 daya sun 2026-04-07 11/550 2026-04-13 10:12 by fenglj492
[ÕÒ¹¤×÷] ɽ¶«¸ßУ½Ìʦ¿¼ºË³¬¼¶ÎÞµ×Ïߣ¬Ô±¹¤¹ý²»ÏÂÈ¥À² +4 qut2026 2026-04-09 9/450 2026-04-12 00:54 by qut2026
[¿¼ÑÐ] 298Çóµ÷¼Á +5 ²ÐºÉÐÂÁø 2026-04-07 5/250 2026-04-11 11:02 by ×ÏêØ×ÏÆå
[¿¼ÑÐ] Çóµ÷¼Á +6 archer.. 2026-04-09 8/400 2026-04-11 10:55 by zhq0425
[¿¼ÑÐ] 288Çóµ÷¼Á +15 ´úfish 2026-04-09 16/800 2026-04-11 10:26 by wwj2530616
[¿¼ÑÐ] ũҵ¹ÜÀí302·ÖÇóµ÷¼Á +3 xuening1 2026-04-10 3/150 2026-04-11 10:18 by zhq0425
[¿¼ÑÐ] ²ÄÁÏÀà284µ÷¼Á +40 Ïë»»ÊÖ»ú²»Ïë½âÊ 2026-04-08 48/2400 2026-04-10 23:28 by 314126402
[¿¼ÑÐ] 085800 ÄÜÔ´¶¯Á¦Çóµ÷¼Á +6 °¢biu°¡°¡°¡°¡°¡ 2026-04-10 6/300 2026-04-10 15:03 by hemengdong
[¿¼ÑÐ] Òѵ÷¼Á +18 ²ñ¿¤Ã¨_ 2026-04-09 19/950 2026-04-09 22:10 by ²ñ¿¤Ã¨_
[¿¼ÑÐ] 332£¬085601Çóµ÷¼Á +12 ydfyh 2026-04-09 14/700 2026-04-09 17:28 by wp06
[¿¼ÑÐ] ²ÄÁÏ307·ÖÇó´óÀÐ×éÊÕÁô +17 Hllºú 2026-04-07 17/850 2026-04-09 10:53 by liuhuiying09
[¿¼ÑÐ] 286Çóµ÷¼Á +19 Faune 2026-04-08 20/1000 2026-04-09 08:36 by ŶŶ123
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û