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RESEARCH POSITION AVAILABLE Wenzhou Institute of Biomaterials and Engineering, WIBE (/https://www.wibe.ac.cn/) is recruiting research staff to take part in a research programme on development of a highly ordered 3D protein-based hydrogel platform for liver tissue analogues and drug screening applications. Requirements: Master or Ph.D. degree in cell biology. Research experience in primary hepatocyte culture (or liver tissue engineering) would be advantageous. Candidate should have experience in primary cell culture and characterization techniques (PCR, immunohistochemistry, and confocal microscopy) related to the above field. The candidate is expected to oversee the progress of various related projects and to be involved in preparing manuscripts for submission to English language peer-reviewed journals. Qualified applicants are invited to send their applications to the emails below. Please submit your detailed resume containing research publications and a summary of your research experience. Contact: Dr. Lee, Bae Hoon (email: bhlee@wibe.ac.cn) or Jing Zheng (Phone: 18358483180; email: zhengj@nimte.ac.cn) or Zhu Mengxiang (Phone:15717325085 email: 373100227@qq.com) We regret that only shortlisted candidates will be notified. Colloidal templating of highly ordered gelatin methacryloyl-based hydrogel platforms for three-dimensional tissue analogues Bae Hoon Lee, Hitomi Shirahama, Myung Hee Kim, Jae Ho Lee, Nam-Joon Cho and Lay Poh Tan NPG Asia Mater 9: e412; doi:10.1038/am.2017.126 We demonstrate the fabrication of three-dimensional, highly ordered protein-based hydrogel platforms for tissue engineering applications. The combination of colloidal templating microfabrication strategies and highly substituted, photocrosslinkable gelatin methacryloyl (GelMA) protein allowed us to fabricate inverted colloidal crystal (ICC) scaffolds with uniform pore interconnectivity, high structural stability and tailorable degradation properties. The resulting scaffolds provided cell attachment sites and promoted intercellular interaction among hepatocytes, which resulted in improved cell function compared to a flat, two-dimensional system. The results demonstrate the potential of GelMA ICC scaffolds to become an effective tissue engineering platform for drug screening and regenerative medicine applications.[ À´×Ô°æ¿éȺ Õã½ ] |
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