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上帝也疯狂(lazy锦溪代发): 金币+5, 协助结帖，感谢应助！ 2016-03-26 13:34:59
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Coating PAMAM dendrimer onto PDMS microfluidic chip to resist nonspecific Biomolecules adsorption
作者:Lin, D (Lin, Dong)[ 1 ] ; Zhao, Q (Zhao, Qin)[ 2 ] ; Yan, MM (Yan, Miaomiao)[ 1 ] ; Hou, GG (Hou, Giuge)[ 1 ]
编者:Kim, YH
PROCEEDINGS OF THE 2015 INTERNATIONAL CONFERENCE ON ADVANCED ENGINEERING MATERIALS AND TECHNOLOGY
丛书: AER-Advances in Engineering Research
卷: 38  页: 204-208
出版年: 2015
会议名称
会议: 5th International Conference on Advanced Engineering Materials and Technology (AEMT)
会议地点: Guangzhou, PEOPLES R CHINA
会议日期: AUG 22-23, 2015
摘要
The surface of poly(dimethylsiloxane)(PDMS) microfluidic chips were modified using polyamidoamine (PAMAM) dendrimer via physical coating. The results showed that the surface of the modified chips was coated by a dense, uniform, continuous, hydrophilicity layer of PAMAM. The hydrophilic of the chip surface was markedly improved. The contact angle of the chips modified decreased from 108.9 degrees to 46.1 degrees. Adenosine and L-lysine were separated via the modified PDMS microfluidic chips. Compared with unmodified chips, the modified chips successfully separated the two biomolecules. The separation efficiencies of adenosine and L-lysine were 7.19x10(4) Plates/m and 8.111x10(4) Plates/m respectively, and the resolutions(R-S) was 4.03. This research may provide a new and effective method to resist nonspecific adsorptionon the PDMS surface and the application of PDMS microfluidic chips in the determination of trace biomolecules.
关键词
作者关键词AMAM dendrimer; microfluidic chip; caoting; hydrophilicity; adsorption
KeyWords Plus:SURFACE MODIFICATION
作者信息
通讯作者地址: Lin, D (通讯作者)
              Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China.
地址:
              [ 1 ] Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
显示增强组织信息的名称        [ 2 ] Ludong Univ, Coll Food Engn, Yantai 264025, Peoples R China
电子邮件地址:lindong3503@163.com; candyffff@163.com; 342302878@qq.com; guigehou@163.com
出版商
ATLANTIS PRESS, 29 AVENUE LAVMIERE, PARIS, 75019, FRANCE
类别 / 分类
研究方向:Engineering; Materials Science
Web of Science 类别:Engineering, Multidisciplinary; Engineering, Manufacturing; Materials Science, Multidisciplinary
文献信息
文献类型roceedings Paper
语种:English
入藏号: WOS:000365261400041
ISBN:978-94-6252-108-7
ISSN: 2352-5401
其他信息
IDS 号: BD9TJ
Web of Science 核心合集中的 "引用的参考文献": 7
Web of Science 核心合集中的 "被引频次": 0
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