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×÷ÕߣºJiasharete Jielile, Minawa Aibai, Gulnur Sabirhazi, Nuerai Shawutali, Wulanbai Tangkejie, Aynaz Badelhan, Yeermike Nuerduola, Turde Satewalede, Darehan Buranbai, Beicen Hunapia, Ayidaer Jialihasi, Jingping Bai, Murat Kizaibek
ÌâÄ¿£ºActive Achilles tendon kinesitherapy accelerates Achilles tendon repair by promoting neurite regeneration
³ö°æÔ´£ºNeural Regeneration Research, 2012, 7(35): 2801.

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Active Achilles tendon kinesitherapy accelerates Achilles tendon repair by promoting neurite regeneration
×÷Õß:Jielile, J (Jielile, Jiasharete)[ 1,2 ] ; Aibai, M (Aibai, Minawa)[ 3 ] ; Sabirhazi, G (Sabirhazi, Gulnur)[ 4 ] ; Shawutali, N (Shawutali, Nuerai)[ 1,2 ] ; Tangkejie, W (Tangkejie, Wulanbai)[ 1,2 ] ; Badelhan, A (Badelhan, Aynaz)[ 1,2 ] ; Nuerduola, Y (Nuerduola, Yeermike)[ 1,2 ] ; Satewalede, T (Satewalede, Turde)[ 1,2 ] ; Buranbai, D (Buranbai, Darehan)[ 1,2 ] ; Hunapia, B (Hunapia, Beicen)[ 1,2 ] ; Jialihasi, A (Jialihasi, Ayidaer)[ 1,2 ] ; Bai, JP (Bai, Jingping)[ 5 ] ; Kizaibek, M (Kizaibek, Murat)[ 6 ] ¸ü¶àÄÚÈݸüÉÙÄÚÈÝ


NEURAL REGENERATION RESEARCH


¾í: 7
ÆÚ: 35
Ò³: 2801-2810
DOI: 10.3969/j.issn.1673-5374.2012.35.008

³ö°æÄê: DEC 15 2012

²é¿´ÆÚ¿¯ÐÅÏ¢

NEURAL REGENERATION RESEARCH  

³ö°æÉÌ SHENYANG EDITORIAL DEPT NEURAL REGENERATION RES, PO BOX 1234, SHENYANG, LIAONING 110004, PEOPLES R CHINA

ISSN: 1673-5374

Ñо¿ÁìÓò Cell Biology
Neurosciences & Neurology



ÕªÒª
Active Achilles tendon kinesitherapy facilitates the functional recovery of a ruptured Achilles tendon. However, protein expression during the healing process remains a controversial issue. New Zealand rabbits, aged 14 weeks, underwent tenotomy followed immediately by Achilles tendon microsurgery to repair the Achilles tendon rupture. The tendon was then immobilized or subjected to postoperative early motion treatment (kinesitherapy). Mass spectrography results showed that after 14 days of motion treatment, 18 protein spots were differentially expressed, among which, 12 were up-regulated, consisting of gelsolin isoform b and neurite growth-related protein collapsing response mediator protein 2. Western blot analysis showed that gelsolin isoform b was up-regulated at days 7-21 of motion treatment. These findings suggest that active Achilles tendon kinesitherapy promotes the neurite regeneration of a ruptured Achilles tendon and gelsolin isoform b can be used as a biomarker for Achilles tendon healing after kinesitherapy.

¹Ø¼ü´Ê
×÷Õ߹ؼü´Ê:achilles tendon rupture; early; motion; functional exercise; exercise; Achilles tendon; healing; proteomics; marker; tissue repair

KeyWords Plus:SURGICAL REPAIR; FUNCTIONAL TREATMENT; KEY REGULATORS; RUPTURE; PROTEINS; GELSOLIN; CRMP-2; REHABILITATION; IMMOBILIZATION; WEIGHTBEARING

×÷ÕßÐÅÏ¢
ͨѶ×÷ÕßµØÖ·: Bai, JP (ͨѶ×÷Õß) Xinjiang Med Univ, Teaching Hosp 3, Dept Orthoped, 30 Beijing S Rd, Urumqi 830011, Xinjiang Uyghur, Peoples R China.
  ÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ
    Xinjiang Medical University  


µØÖ·:  [ 1 ] Xinjiang Med Univ, Teaching Hosp 1, Dept Microsurg Repair & Reconstruct, Urumqi 830054, Xinjiang Uyghur, Peoples R China
  ÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ
    Xinjiang Medical University  
       [ 2 ] Res Inst Orthoped Xinjiang Uyghur Autonomous Reg, Sports Med Res Ctr, Urumqi 830054, Xinjiang Uyghur, Peoples R China
       [ 3 ] Urumqi Ctr Dis Control & Prevent, Urumqi 830026, Xinjiang Uyghur, Peoples R China
[ 4 ] Chinese Acad Sci, Xinjiang Inst Ecol & Geog, Urumqi 830011, Xinjiang Uyghur, Peoples R China
  ÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ
    Chinese Academy of Sciences  
[ 5 ] Xinjiang Med Univ, Teaching Hosp 3, Dept Orthoped, Urumqi 830011, Xinjiang Uyghur, Peoples R China
  ÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ
    Xinjiang Medical University  
       [ 6 ] Res Inst Kazakh Tradit Med Ili Kazakh Autonomous, Yining 835000, Ili Kazakh Auto, Peoples R China


µç×ÓÓʼþµØÖ·:jingping_bai@163.com

»ù½ð×ÊÖúÖÂл
»ù½ð×ÊÖú»ú¹¹ ÊÚȨºÅ
National Natural Science Foundation of China  30760256  
²é¿´»ù½ð×ÊÖúÐÅÏ¢¹Ø±Õ»ù½ð×ÊÖúÐÅÏ¢   

This study was financially supported by the National Natural Science Foundation of China, No. 30760256.

³ö°æÉÌ
SHENYANG EDITORIAL DEPT NEURAL REGENERATION RES, PO BOX 1234, SHENYANG, LIAONING 110004, PEOPLES R CHINA

Àà±ð / ·ÖÀà
Ñо¿·½Ïò:Cell Biology; Neurosciences & Neurology

Web of Science Àà±ð:Cell Biology; Neurosciences

ÎÄÏ×ÐÅÏ¢
ÎÄÏ×ÀàÐÍ:Article

ÓïÖÖ:English

Èë²ØºÅ: WOS:000313148100008

PubMed ID: 25317130

ISSN: 1673-5374

ÆäËûÐÅÏ¢
IDS ºÅ: 065KV

Web of Science ºËÐĺϼ¯ÖÐµÄ "ÒýÓõIJο¼ÎÄÏ×": 51

Web of Science ºËÐĺϼ¯ÖÐµÄ "±»ÒýƵ´Î": 2

Ó°ÏìÒò×Ó 0.22  0.205  
2014  5 Äê  


JCR® Àà±ð Àà±ðÖеÄÅÅÐò JCR ·ÖÇø
CELL BIOLOGY  182/184  Q4
NEUROSCIENCES  247/252  Q4


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