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However, the size was smaller than that measured by DLS. This was mainly due to the process involved in the preparation of sample. In the case of the TEM and SEM methods, TEM and SEM images depicted the actual size at the dried state of sample, whereas the size measured by the laser light scattering method was a hydrodynamic diameter (hydrated state), and therefore the nanoparticles showed a larger hydrodynamic volume due to solvent effect in the hydrated state. À´Ô´£ºThe potential of self-assembled, pH-responsive nanoparticles of mPEGylated peptide dendron¨Cdoxorubicin conjugates for cancer therapy |
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ÕâÊÇÔÙÕý³£²»¹ýµÄÏÖÏó°¡ researchgateÉÏÓÐÒ»¸öÈ˽âÊ͵Ĵ𰸠DLS gives a hydrodynamic size that corresponds to the core and the swollen corona of the micelles, whereas TEM often gives a size of the core for micelles in a dried state as the corona with low electronic density is not visible. |
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