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sapphires008

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[求助] 请帮我查下web of science 是否能检索到这篇文章,pubmed上已经可以检索到

请帮我查下web of science 是否能检索到这篇文章,pubmed上已经可以检索到:
Lei F, Gao Y, Liu F, Hou R, Cai RL, and Qi Y. Shuang-Huang-Lian Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice Involving Anti-Inflammatory and Antioxidative Activities. Evid Based Complement Alternat Med, 2015, doi: 10.1155/2015/283939.
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sapphires008: 金币+15, ★★★★★最佳答案, 谢谢! 2015-06-11 08:02:48
心静_依然: LS-EPI+1, 感谢应助 2015-06-11 08:34:15
Shuang-huang-lian attenuates lipopolysaccharide-induced acute lung injury in mice involving anti-inflammatory and antioxidative activities.

作者:Fang, Lei; Gao, Yuan; Liu, Fen; Hou, Rui; Cai, Run-Lan; Qi, Yun

Evidence-based complementary and alternative medicine : eCAM

卷:2015

页:283939

DOI:10.1155/2015/283939

出版年:2015 (Epub 2015 Apr 06)
摘要

Shuang-Huang-Lian (SHL) is a common traditional Chinese preparation extracted from Lonicerae Japonicae Flos, Scutellariae Radix, and Fructus Forsythiae. In this study, we demonstrate the anti-inflammatory and antioxidative effects of SHL on lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in mice. SHL reduced the lung wet/dry weight ratio, lowered the number of total cells in the bronchoalveolar lavage fluid, and decreased the myeloperoxidase activity in lung tissues 6h after LPS treatment. It also inhibited the overproduction of proinflammatory cytokines (TNF-alpha, IL-1beta, and IL-6) in the bronchoalveolar lavage fluid. Histological studies demonstrated that SHL attenuated LPS-induced interstitial edema, hemorrhage, and the infiltration of neutrophils into the lung tissue. Moreover, SHL could also enhance the superoxide dismutase and catalase activities, increase the reduced glutathione content, and decrease the malondialdehyde content. The present results suggest that SHL possesses anti-inflammatory and antioxidative properties that may protect mice against LPS-induced ALI.

作者信息

地址:Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
文献信息

文献类型:Journal Article

语种:English

PubMed ID:25945107

NLM 唯一 ID:101215021

创建日期: 06 May 2015     完成日期: 06 May 2015     修订日期: 08 May 2015

电子出版:06 Apr 2015

国家/地区: United States

ISSN:1741-427X
期刊信息

    Impact Factor (影响因子): Journal Citation Reports®

其他信息

记录所有者:NLM

状态ubMed-not-MEDLINE
2楼2015-06-10 22:32:22
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sapphires008

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一叶浮萍归大海,人生何处不相逢
3楼2015-06-11 09:54:43
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