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暮云深

金虫 (小有名气)

[求助] 请老师帮我看看这2个句子,有没有错误。帮我润色一下。

1.PGE2 is synthesized from eicosatetraenoic acids in the presence of cyclooxygenase and its level in the fluid of knee joints in OA is overexpression. Previous study showed that PGE2 could improve the concentration of intracellular cAMP and then activating protein kinase A to induce articular chondrocyte apoptosis。
2.The model of experimental OA in vivo is characterized by degradation of articular cartilage to repeat the circumstances of OA patients. The articular chondrocytes apoptosis is responsible for the degradation of articular cartilage. The models which mimic articular chondrocytes apoptosis in vitro to lead articular cartilage degradation are valuable in the evaluation of pathogenesis and therapeutic methods of OA。

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genhunter

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暮云深: 金币+30, 翻译EPI+1, ★★★★★最佳答案 2015-05-21 12:59:29
暮云深(RXMCDM代发): 金币+10 2015-05-24 23:46:06
1.PGE2 is synthesized by cyclooxygenase from eicosatetraenoic acids  and its level in the fluid of knee joints in OA is highly elevated. It is known that PGE2 activates its receptor,  increases the concentration of intracellular cAMP and then activates protein kinase A, which leads to apoptosis of articular chondrocytes。
2. The in vivo  experimental  model of OA  is characterized by the degradation of articular cartilage mimicking the circumstances of OA patients.  Also known is the fact that the apoptosis of articular chondrocytes is responsible for the degradation of articular cartilage.  A treatment that leads to articular chondrocytes apoptosis in vitro and a condition that prevent such events are valuable both for mechanism studies of pathogenesis and developing new therapeutic interventions of OA。
离成功还差一点
2楼2015-05-21 09:24:03
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genhunter

至尊木虫 (著名写手)

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fluid of knee joints也叫synovial fluid, 炎症时不光articular chondrocytes, synoviacytes增生与活化也是重要环节。
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3楼2015-05-21 09:28:15
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genhunter

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上次漏了后半句,发给你邮箱了。
离成功还差一点
4楼2015-05-21 09:42:57
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武汉一心一译

捐助贵宾 (著名写手)


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1.【PGE2 is 去掉】 synthesized from eicosatetraenoic acids in the presence of cyclooxygenase 【and its 去掉】 [PGE2 shows an overexpressed 某某level】 【level建议写明是什么level】 in the fluid of knee joints in OA 【is overexpression去掉】. Previous study [studies] showed that PGE2 could [played an role in] improve [improving] the concentration of intracellular cAMP and [then 去掉] activating protein kinase A 【to induce 改成 for inducing】 articular chondrocyte apoptosis.

2.The model of experimental OA in vivo is characterized by 【the repeated】 circumstances of OA patients【due to the degradation of articular cartilage, which is caused by articular chondrocytes apoptosis】. The models 【by】which mimic articular chondrocytes apoptosis in vitro 【to 去掉】lead articular cartilage degradation are valuable in the evaluation of pathogenesis and therapeutic methods of OA
5楼2015-05-21 11:31:38
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