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We compared the amount of adsorbed fibrinogen from human plasma on unmodified and modified PHBV surfaces. Figure 6 exhibits that the unmodified hydrophobic PHBV surface attracts the most amount of fibrinogen among the four types of different PHBV films. In more detail, the amount of fibrinogen adsorbed on NH3 plasma-treated surfaces was ¡«10% less than that adsorbed on unmodified surfaces. Actually, there was no statistically significant difference in fibrinogen adsorption between these two surfaces. After the linkage of PEG-containing cross-linkers, the adsorbed amount of fibrinogen on PHBV-PEGMA surfaces decreased by 40% from that on unmodified surfaces because of the nonfouling properties of the introduced PEG chains. |
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Malyhon: ½ð±Ò+10, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸ 2015-03-07 12:33:49
Malyhon: ½ð±Ò+10, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸ 2015-03-07 12:33:49
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We compared the amount of adsorbed fibrinogen from human plasma on unmodified and modified PHBV surfaces. Figure 6 exhibits that the unmodified hydrophobic PHBVsurface attracts the most amount of fibrinogen among the four types of different PHBV films. In more detail, the amount of fibrinogen adsorbed on NH3 plasma-treated surfaces was ¡«10% less than that adsorbed on unmodified surfaces. Actually, there was no statistically significant difference in fibrinogen adsorption between these two surfaces. After the linkage of PEG-containing cross-linkers, the adsorbed amount of fibrinogen on PHBV-PEGMA surfaces decreased by 40% from that onunmodified surfaces because of the nonfouling properties of the introduced PEG chains. ÎÒÃDZȽÏÁËÈËѪ½¬ÏËάµ°°×ÔÔÚ±íÃæÐÞÊκóºÍδ¾ÐÞÊεÄPHBV±íÃæµÄÎü¸½Á¿¡£Í¼6ÏÔʾδ¾ÐÞÊεÄÊèË®ÐÔPHBVÔÚËÄÖÖ²»Í¬µÄPHBV±¡Ä¤ÖÐÏËάµ°°×ÔÎü¸½Á¿×î´ó¡£¾ßÌåµØËµ£¬Óð±ÆøµÈÀë×Ó´¦ÀíºóµÄ±íÃæ±Èδ¾ÐÞÊεÄÊèË®ÐÔµÄPHBVµÄÎü¸½Á¿µÍ10%, µ«Á½Õß¼ä²îÒìÎÞͳ¼ÆÒâÒå¡£¾º¬PEGµÄ½»Áª¼ÁÓçºÏÒÔºó, µ¼ÈëµÄ¾ÛÒÒ¶þ´¼Á´¸³Ó迹Îü¸½ÌØÕ÷£¬ÏËάµ°°×ÔÔÚPHBV-PEGMA±íÃæÎü¸½Á¿±Èδ¾ÐÞÊεÄPHBV½µµÍÁË40%¡£ |

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