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[求助] 帮忙查一篇论文的检索号和他引情况

Xian-Qing Deng, zheng-Qi Dong, Ming-Xia Song, Bing Shu, Shi-Ben Wang, and Zhe-Shan Quan. Synthesis and Anticonvulsant Activities of Some Triazolothiadiazole Derivatives. ARCH PHARM, 2012, 345: 565–573.
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songmingxia: 金币+4, ★★★★★最佳答案, 非常感谢！！！ 2014-09-20 12:14:56
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被引频次: 6
https://apps.webofknowledge.com/ ... c-8f45-2e9ed8ee98dc





1.






1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry

作者: Hu, Yang; Li, Cui-Yun; Wang, Xiao-Ming; 等.

CHEMICAL REVIEWS  卷: 114   期: 10   页: 5572-5610   出版年: MAY 28 2014

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被引频次: 0
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2.






Synthesis and evaluation of the anticonvulsant activity of 8-alkoxy-4,5-dihydrobenzo[1,2,4]triazolo[4,3-d][1,4]thiazepine derivatives

作者: Deng, Xian-Qing; Song, Ming-Xia; Wang, Shi-Ben; 等.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY  卷: 29   期: 2   页: 272-280   出版年: APR 2014

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被引频次: 0
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3.






N-(5-Mercapto-1,3,4-Thiadiazol-2-yl)-2-Phenylacetamide Derivatives: Synthesis and In-vitro Cytotoxicity Evaluation as Potential Anticancer Agents

作者: Mohammadi-Farani, Ahmad; Heidarian, Neda; Aliabadi, Alireza

IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH  卷: 13   期: 2   页: 487-492   出版年: SPR 2014





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被引频次: 0
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4.






Discovery of 2-Phenyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide Derivatives as Apoptosis Inducers via the Caspase Pathway with Potential Anticancer Activity

作者: Hosseinzadeh, Leila; Khorand, Amanc; Aliabadi, Alireza

ARCHIV DER PHARMAZIE  卷: 346   期: 11   页: 812-818   出版年: NOV 2013

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被引频次: 1
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5.






Design, synthesis and antidepressant activity evaluation 2'-hydroxy-4',6'-diisoprenyloxychalcone derivatives

作者: Guan, Li-Ping; Zhao, Dong-Hai; Chang, Yue; 等.

MEDICINAL CHEMISTRY RESEARCH  卷: 22   期: 11   页: 5218-5226   出版年: NOV 2013

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被引频次: 2
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6.






Synthesis and antimicrobial activity of new 1,3,4-thiadiazoles containing oxadiazole, thiadiazole and triazole nuclei

作者: Maddila, Suresh; Jonnalagadda, Sreekanth B.

PHARMACEUTICAL CHEMISTRY JOURNAL  卷: 46   期: 11   页: 661-666   出版年: FEB 2013

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songmingxia: 金币+2, ★★★很有帮助, 谢谢啦 2014-09-20 12:15:32
Synthesis and Anticonvulsant Activities of Some Triazolothiadiazole Derivatives


作者eng, XQ (Deng, Xian-Qing)[ 1 ] ; Dong, ZQ (Dong, Zheng-Qi)[ 2,3 ] ; Song, MX (Song, Ming-Xia)[ 1 ] ; Shu, B (Shu, Bing)[ 1 ] ; Wang, SB (Wang, Shi-Ben)[ 1 ] ; Quan, ZS (Quan, Zhe-Shan)[ 1 ]




ARCHIV DER PHARMAZIE



卷: 345

期: 7

页: 565-573

DOI: 10.1002/ardp.201100326

出版年: JUL 2012

查看期刊信息










































摘要

The present study describes the synthesis and anticonvulsant activity evaluation of 6-substituted-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives (4a4x) and their partially dehydrogenated products 5,6-dihydro-6-substituted-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives (5a5n). The bioevaluation demonstrated that most compounds in the series of 4a4x exhibited potent anticonvulsant activity in the maximal electroshock test. Among which, 6-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (4h) emerged as the most promising candidate on the basis of its favorable ED50 value of 23.7?mg/kg and PI value of 10.8. In addition, the potency of compound 4h against seizures induced by pentylenetetrazole, 3-mercaptopropionic acid, and bicuculline in the chemical-induced seizure tests suggested that compound 4h displayed broad-spectrum activity in several models, and it may exert its anticonvulsant activity through affecting the GABAergic system.


关键词

作者关键词:Anticonvulsant; Maximal electroshock; Pentylenetetrazole; Synthesis; Triazolothiadiazole

KeyWords Plus:ANTIEPILEPTIC DRUGS; ANTI-HIV; EPILEPSY; GABA; ANTAGONISM; SEIZURES; ANALOGS


作者信息

通讯作者地址: Quan, ZS (通讯作者)





Yanbian Univ, Coll Pharm, 977 Pk Rd, Yanji 133002, Jilin, Peoples R China.





地址:





[ 1 ] Yanbian Univ, Coll Pharm, Yanji 133002, Jilin, Peoples R China







[ 2 ] Peking Union Med Coll, Beijing 100021, Peoples R China







[ 3 ] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100730, Peoples R China






电子邮件地址:zsquan@ybu.edu.cn


基金资助致谢



基金资助机构

授权号



National Natural Science Foundation of China


81160382

查看基金资助信息   




出版商

WILEY-V C H VERLAG GMBH, BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY


类别 / 分类

研究方向harmacology & Pharmacy; Chemistry

Web of Science 类别:Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy


文献信息

文献类型:Article

语种:English

入藏号: WOS:000305986000008

ISSN: 0365-6233


期刊信息


Impact Factor (影响因子): Journal Citation Reports®


其他信息

IDS 号: 968MO

Web of Science 核心合集中的 "引用的参考文献": 29

Web of Science 核心合集中的 "被引频次": 6









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入藏号: WOS:000305986000008
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