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dreamer2001ly木虫 (正式写手)
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[求助]
求助web of science检索
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| 求哪位朋友帮忙用ISI web of science检索一下这篇论文Analysis of ADAM17 Polymorphisms and Susceptibility to Sporadic Abdominal Aortic Aneurysm（Cell Physiol Biochem 2014;33:1426-1438）是否被SCI收录？谢谢。 |
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baiyuefei
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风雪
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2楼2014-08-15 08:29:07
baiyuefei
版主 (文学泰斗)
风雪
- LS-EPI: 1647
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【答案】应助回帖
★ ★ ★ ★ ★
dreamer2001ly: 金币+5, ★★★★★最佳答案 2014-08-15 10:39:46
sunshan4379: 检索EPI+1, 感谢应助！ 2014-08-15 10:42:14
dreamer2001ly: 金币+5, ★★★★★最佳答案 2014-08-15 10:39:46
sunshan4379: 检索EPI+1, 感谢应助！ 2014-08-15 10:42:14
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Analysis of ADAM17 Polymorphisms and Susceptibility to Sporadic Abdominal Aortic Aneurysm 作者:Li, Y (Li, You)[ 1 ] ; Yang, C (Yang, Cheng)[ 2 ] ; Ma, GD (Ma, Guoda)[ 1 ] ; Cui, LL (Cui, Lili)[ 1 ] ; Gu, XF (Gu, Xuefeng)[ 1 ] ; Chen, YY (Chen, Yanyan)[ 1 ] ; Zhao, B (Zhao, Bin)[ 1,3 ] ; Wang, HY (Wang, Haiyang)[ 4 ] ; Li, KS (Li, Keshen)[ 1 ] CELLULAR PHYSIOLOGY AND BIOCHEMISTRY 卷: 33 期: 5 页: 1426-1438 DOI: 10.1159/000358708 出版年: 2014 查看期刊信息 摘要 Background: Accumulating evidence suggests that the principal TNF-alpha converting enzyme, a disintegrin and metalloproteinase 17 (ADAM17), is involved in the development of human abdominal aortic aneurysm (AAA). However, the association between ADAM17 gene polymorphisms and AAA has not been explored. The present study was aimed to determine the association between ADAM17 promoter polymorphisms and AAA. Methods: A total of 316 patients with AAA and 306 age-matched healthy controls were enrolled in this study. Two ADAM17 promoter polymorphisms (rs12692386 and rs1524668) were determind. Real-time PCR was employed to detect the expression of ADAM17. Results: Overall, there was a significant difference in the frequency of the genotype rs12692386 between the AAA and control subjects (P=0.0096). Furthermore, men with the rs12692386 AG genotype conferred a higher risk of developing AAA (P=0.0058). Additionally, the rs12692386 mutated AG genotype of ADAM17 was significantly associated with increased ADAM17 expression (P=0.035) and TNF-alpha production (P=0.042) in AAA patients. In contrast, the allele frequency of rs1524668 was not statistically associated with AAA. Conclusions: Our findings indicate a positive association between the rs12692386 polymorphism of ADAM17 and AAA. This new knowledge about ADAM17 identifies a role for ADAM17 in the pathophysiology of AAA and has important clinical implications with regard to potential therapeutics. Copyright (C) 2014 S. Karger AG, Basel 关键词 作者关键词:ADAM17; Abdominal aortic aneurysm; Polymorphism KeyWords Plus:ALPHA CONVERTING-ENZYME; GENOME-WIDE ASSOCIATION; E-DEFICIENT MICE; TNF-ALPHA; ANGIOTENSIN-II; NITRIC-OXIDE; VARIANT; METALLOPROTEINASES; ATHEROSCLEROSIS; SURVEILLANCE 作者信息 通讯作者地址: Li, KS (通讯作者) Guangdong Med Coll, Affiliated Hosp, Guangdong Key Lab Age Related Cardiac & Cerebral, Zhanjiang 524001, Peoples R China. 地址: [ 1 ] Guangdong Med Coll, Affiliated Hosp, Guangdong Key Lab Age Related Cardiac & Cerebral, Zhanjiang 524001, Peoples R China [ 2 ] Fu Dan Univ, Dept Cardiac Surg, Zhong Shan Hosp, Shanghai Inst Cardiovasc Dis, Shanghai, Peoples R China [ 3 ] Guangdong Med Coll, Affiliated Hosp, Inst Neurol, Zhanjiang 524001, Peoples R China [ 4 ] Harbin Med Univ, Affiliated Hosp 1, Dept Vasc Surg Gen Surg, Harbin 150001, Heilongjiang, Peoples R China 电子邮件地址:haiyangwang811@163.com; likeshen1971@126.com 基金资助致谢 基金资助机构 授权号 National Nature Science Foundation of China 31171219 81271213 81070878 81271214 81300929 81261120404 Natural Science Foundation of Guangdong Province, China S2012010008222 Science and Technology Innovation Fund of Guangdong Medical College STIF 201101 查看基金资助信息 出版商 KARGER, ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND 类别 / 分类 研究方向:Cell Biology; Physiology Web of Science 类别:Cell Biology; Physiology 文献信息 文献类型:Article 语种:English 入藏号: WOS:000336493300016 ISSN: 1015-8987 电子 ISSN: 1421-9778 期刊信息 Impact Factor (影响因子): Journal Citation Reports® 其他信息 IDS 号: AH9VQ Web of Science 核心合集中的 "引用的参考文献": 41 Web of Science 核心合集中的 "被引频次": 0 引文网络 0 被引频次 41 引用的参考文献 查看 Related Records 查看引证关系图 创建引文跟踪 (数据来自 Web of ScienceTM 核心合集) 全部被引频次计数 0 / 所有数据库 0 / Web of Science 核心合集 0 / BIOSIS Citation Index 0 / 中国科学引文数据库 0 / Data Citation Index 0 / SciELO Citation Index 此记录来自: Web of ScienceTM 核心合集 在其他数据库中查看记录: 查看 医学数据 (在 MEDLINE® 中) 建议修正 如果希望提高此记录中数据的质量，请提供修正建议。 |
3楼2014-08-15 08:29:24
dreamer2001ly
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4楼2014-08-15 10:40:04
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