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dreamer2001ly

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[求助] 求助web of science检索

求哪位朋友帮忙用ISI web of science检索一下这篇论文Analysis of ADAM17 Polymorphisms and Susceptibility to Sporadic Abdominal Aortic Aneurysm（Cell Physiol Biochem 2014;33:1426-1438）是否被SCI收录？谢谢。
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感谢参与，应助指数 +1
https://apps.webofknowledge.com/ ... age=1&doc=1
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2楼2014-08-15 08:29:07
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dreamer2001ly: 金币+5, ★★★★★最佳答案 2014-08-15 10:39:46
sunshan4379: 检索EPI+1, 感谢应助！ 2014-08-15 10:42:14
Analysis of ADAM17 Polymorphisms and Susceptibility to Sporadic Abdominal Aortic Aneurysm


作者:Li, Y (Li, You)[ 1 ] ; Yang, C (Yang, Cheng)[ 2 ] ; Ma, GD (Ma, Guoda)[ 1 ] ; Cui, LL (Cui, Lili)[ 1 ] ; Gu, XF (Gu, Xuefeng)[ 1 ] ; Chen, YY (Chen, Yanyan)[ 1 ] ; Zhao, B (Zhao, Bin)[ 1,3 ] ; Wang, HY (Wang, Haiyang)[ 4 ] ; Li, KS (Li, Keshen)[ 1 ]




CELLULAR PHYSIOLOGY AND BIOCHEMISTRY



卷: 33

期: 5

页: 1426-1438

DOI: 10.1159/000358708

出版年: 2014

查看期刊信息





































摘要

Background: Accumulating evidence suggests that the principal TNF-alpha converting enzyme, a disintegrin and metalloproteinase 17 (ADAM17), is involved in the development of human abdominal aortic aneurysm (AAA). However, the association between ADAM17 gene polymorphisms and AAA has not been explored. The present study was aimed to determine the association between ADAM17 promoter polymorphisms and AAA. Methods: A total of 316 patients with AAA and 306 age-matched healthy controls were enrolled in this study. Two ADAM17 promoter polymorphisms (rs12692386 and rs1524668) were determind. Real-time PCR was employed to detect the expression of ADAM17. Results: Overall, there was a significant difference in the frequency of the genotype rs12692386 between the AAA and control subjects (P=0.0096). Furthermore, men with the rs12692386 AG genotype conferred a higher risk of developing AAA (P=0.0058). Additionally, the rs12692386 mutated AG genotype of ADAM17 was significantly associated with increased ADAM17 expression (P=0.035) and TNF-alpha production (P=0.042) in AAA patients. In contrast, the allele frequency of rs1524668 was not statistically associated with AAA. Conclusions: Our findings indicate a positive association between the rs12692386 polymorphism of ADAM17 and AAA. This new knowledge about ADAM17 identifies a role for ADAM17 in the pathophysiology of AAA and has important clinical implications with regard to potential therapeutics. Copyright (C) 2014 S. Karger AG, Basel


关键词

作者关键词:ADAM17; Abdominal aortic aneurysm; Polymorphism

KeyWords Plus:ALPHA CONVERTING-ENZYME; GENOME-WIDE ASSOCIATION; E-DEFICIENT MICE; TNF-ALPHA; ANGIOTENSIN-II; NITRIC-OXIDE; VARIANT; METALLOPROTEINASES; ATHEROSCLEROSIS; SURVEILLANCE


作者信息

通讯作者地址: Li, KS (通讯作者)



      

Guangdong Med Coll, Affiliated Hosp, Guangdong Key Lab Age Related Cardiac & Cerebral, Zhanjiang 524001, Peoples R China.



地址:



      

[ 1 ] Guangdong Med Coll, Affiliated Hosp, Guangdong Key Lab Age Related Cardiac & Cerebral, Zhanjiang 524001, Peoples R China





[ 2 ] Fu Dan Univ, Dept Cardiac Surg, Zhong Shan Hosp, Shanghai Inst Cardiovasc Dis, Shanghai, Peoples R China





      

[ 3 ] Guangdong Med Coll, Affiliated Hosp, Inst Neurol, Zhanjiang 524001, Peoples R China





[ 4 ] Harbin Med Univ, Affiliated Hosp 1, Dept Vasc Surg Gen Surg, Harbin 150001, Heilongjiang, Peoples R China





电子邮件地址:haiyangwang811@163.com; likeshen1971@126.com


基金资助致谢



基金资助机构

授权号



National Nature Science Foundation of China


31171219

81271213

81070878

81271214

81300929

81261120404



Natural Science Foundation of Guangdong Province, China


S2012010008222



Science and Technology Innovation Fund of Guangdong Medical College


STIF 201101

查看基金资助信息   




出版商

KARGER, ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND


类别 / 分类

研究方向:Cell Biology; Physiology

Web of Science 类别:Cell Biology; Physiology


文献信息

文献类型:Article

语种:English

入藏号: WOS:000336493300016

ISSN: 1015-8987

电子 ISSN: 1421-9778


期刊信息


Impact Factor (影响因子): Journal Citation Reports®


其他信息

IDS 号: AH9VQ

Web of Science 核心合集中的 "引用的参考文献": 41

Web of Science 核心合集中的 "被引频次": 0


引文网络




0 被引频次

41 引用的参考文献

查看 Related Records

查看引证关系图

创建引文跟踪

(数据来自 Web of ScienceTM 核心合集)



全部被引频次计数



0 / 所有数据库

0 / Web of Science 核心合集

0 / BIOSIS Citation Index

0 / 中国科学引文数据库

0 / Data Citation Index

0 / SciELO Citation Index



此记录来自:

Web of ScienceTM 核心合集


在其他数据库中查看记录:
查看 医学数据 (在 MEDLINE® 中)


建议修正


如果希望提高此记录中数据的质量，请提供修正建议。
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3楼2014-08-15 08:29:24
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dreamer2001ly

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引用回帖:
3楼: Originally posted by baiyuefei at 2014-08-15 08:29:24
Analysis of ADAM17 Polymorphisms and Susceptibility to Sporadic Abdominal Aortic Aneurysm


作者:Li, Y (Li, You) ; Yang, C (Yang, Cheng) ; Ma, GD (Ma, Guoda) ; Cui, LL (Cui, Lili) ; Gu, XF (Gu, X ...

谢谢
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