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佟玉风银虫 (著名写手)
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[求助]
求翻译一段中文摘要
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HPLC法分析在D-GlaN致急性肝损伤模型大鼠尿液中肋柱花化学成分 摘要:目的:研究肋柱花水煎液在D-GlaN致急性肝损伤模型大鼠尿液中的化学成分。方法:采用腹腔注射D-GlaN制备急性肝损伤大鼠模型;利用HPLC法对大鼠灌胃肋柱花水煎液后尿液中化学成分进行分析,检测波长280nm;流动相为甲醇:水;流速1.0ml/min;柱温35℃;梯度洗脱。结果:在含药尿液中共标识25个峰,3个为药物原型成分,10个为代谢产物;其余为尿液内源性成分。 结论:该方法较全面的分析肋柱花在急性肝损伤模型大鼠尿液中的化学成分,为进一步研究肋柱花药效物质基础提供依据。 关键词:肋柱花;D-GlaN;急性肝损伤模型;尿液;HPLC |
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【答案】应助回帖
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RXMCDM: 金币+1, 多谢应助! 2014-07-09 07:28:27
佟玉风: 金币+50, 翻译EPI+1, ★★★很有帮助 2014-07-09 09:00:58
RXMCDM: 金币+1, 多谢应助! 2014-07-09 07:28:27
佟玉风: 金币+50, 翻译EPI+1, ★★★很有帮助 2014-07-09 09:00:58
abstract:purpose:To study the chemical compositions of Lomatogonium rotatum"s water decoction in the urine of the model rat which was induced acute liver damage by D-GlaN. Method:The model rats were injected by adominal injection of D-GlaN to gain acute liver damage.The chemical compositions in the urine of model rats which were fed Lomatogonium rotatum's water decoction have been analyzed the method of HPLC.The detection wavelength was 280nm.The mobile phase are methanol and water,Flow rate was 1.0ml/min,The column temperature is 35 ℃,Gradient elution,The results, 25 peaks were found in the drug-containing urine. three original ingredients of drug,ten metabolites,the remaining components were the urine-derived ingredients. conclusion: The chemical compositions of Lomatogonium rotatum's water decoction in the urine of the model rat have been analyzed more comprehensive by this method,this method have provided the basis to further study Lomatogonium rotatum.仅供参考 |

2楼2014-07-08 19:21:14
佟玉风
银虫 (著名写手)
- 应助: 2 (幼儿园)
- 金币: 1090.3
- 散金: 120
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- 在线: 41.4小时
- 虫号: 3267129
- 注册: 2014-06-10
- 性别: MM
- 专业: 民族药学
3楼2014-07-09 08:28:20

4楼2014-07-09 08:36:13
佟玉风
银虫 (著名写手)
- 应助: 2 (幼儿园)
- 金币: 1090.3
- 散金: 120
- 红花: 6
- 帖子: 1031
- 在线: 41.4小时
- 虫号: 3267129
- 注册: 2014-06-10
- 性别: MM
- 专业: 民族药学
5楼2014-07-09 08:50:07
佟玉风
银虫 (著名写手)
- 应助: 2 (幼儿园)
- 金币: 1090.3
- 散金: 120
- 红花: 6
- 帖子: 1031
- 在线: 41.4小时
- 虫号: 3267129
- 注册: 2014-06-10
- 性别: MM
- 专业: 民族药学
6楼2014-07-10 09:21:33














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