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自中國的前基督教时代以来, EUO已被古代药典列為“SHANG PIN”。已有記錄超过11146種EUO土著植物�?群作為醫藥用途(神农本草经: The Divine Farmer’s Herb-Root Classic) 。以树皮作為古老滋补的材料已有两千年的歷史，(顯示於中国药典，神农本草经、本草綱沐(本草綱目和中草藥詞典))。後?�,一些科學研究表明葉片提取成分與根莖部相似, 因而?V泛用作代替樹皮為藥。在临床研究中，EUO葉片和樹皮同樣具有多种活性成分，包括环烯醚萜类，木脂素，酚�?，苯丙素，黄酮类，酚酸�?，萜类，與及糖�?,苷�?的相關有機物。所有的化合物具有多种药理活性，?K用治於多種疾病，如抗骨质疏松，抗氧化，抗肥胖，抗突变，抗微生物，抗糖尿病，免疫抑制活性和神经系统调节。本评論文章在於讨论和總結EUO物種於歷史, 化學及藥理方面的最新信息。特别於EUO提取物的潜在藥理機制將提供具體的內容和全新的焦點。 Since the pre-Christian era in China, the EUO was listed as “SHANG PIN” by ancient Chinese pharmacopoeia. It has been recorded over 11,146 indigenous plant taxa as medicinal use. (The Divine Farmer’s Herb-Root Classic from Shennong Bencao Jing) . The bark as Chinese medicinal herbs, with the oldest tonic material for two thousands of years. (By indicating Chinese codex, Shen Nong Ben Cao Jing and Ben Cao Gan Mu (Materia Medica, a dictionary of Chinese herbs)). After that, some scientific research suggest that the part of leaves extract contains chemical components are similar to bark, thus, it was widely used as herbs instead with bark . In clinical studies, they both leaves and bark of EUO has various active components, including iridoid, lignan, phenol, phenylpropanoid, flavonoids, phenolic acid, terpenes, and other from organism, saccharide and glycosides. All of the compounds possess various pharmacological activity, which used in treatment of many diseases, such as anti-osteoporotic, anti-oxidant, anti-obesity, anti-mutagenicity, anti-microbial, anti-diabetic, immunosuppressive activities, and regulation of nervous system. In this review article discussed aims to summarize up-to-date information for histroy, chemistry and pharmacology in EUO species. Especially the pharmacology activity from EUO extracts due the potential mechanisms will provide some new focus and specific content. |
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