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bonny928: 金币+20, thanks~ 2014-06-10 16:05:07
oven1986: 检索EPI+1, 感谢应助！ 2014-06-12 10:15:40
Synthesis and characterization of novel purpurinimides as photosensitizers for photodynamic therapy.
作者:Cui, Bing Cun; Yoon, Il; Li, Jia Zhu; Lee, Woo Kyoung; Shim, Young Key
International journal of molecular sciences
卷:15 期:5 页:8091-105
DOI:10.3390/ijms15058091
出版年:2014 May 08
摘要
A series of novel purpurinimides with long wavelength absorption were designed and synthesized to develop novel and potential photosensitizers. These compounds were investigated through reduction, oxidation, rearrangement reaction and amidation reactions of methyl pheophorbide a. They demonstrated a considerable bathochromic shift of the major absorption band in the red region of the optical spectrum (695-704 nm). Newly synthesized purpurinimides were screened for their antitumor activities, and showed higher photodynamic efficiency against A549 cell lines as compared to purpurin-18 methyl ester. The results revealed the novel purpurinimides could be potential photosensitizers.
作者信息
地址:College of Medicine, Hubei Polytechnic University, Huangshi 435003, China. cuibc928@hotmail.com.
文献信息
文献类型:Journal Article
语种:English
PubMed ID:24815070
NLM 唯一 ID:101092791
创建日期: 12 May 2014
电子出版:08 May 2014
国家/地区: Switzerland
ISSN:1422-0067
期刊信息
Impact Factor (影响因子): Journal Citation Reports®
其他信息
分主题子库:Index Medicus
状态:In-Data-Review |
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